5-Nitroindole-3-carboxylic acid
- CAS No.
- 6958-37-8
- Chemical Name:
- 5-Nitroindole-3-carboxylic acid
- Synonyms
- 5-nitro-1H-indole-3-carboxylic acid;RARECHEM AL BE 1168;5-Nitroindole-3-carboxylic acid;1H-Indole-3-carboxylic acid, 5-nitro-
- CBNumber:
- CB9435674
- Molecular Formula:
- C9H6N2O4
- Molecular Weight:
- 206.15
- MDL Number:
- MFCD06203492
- MOL File:
- 6958-37-8.mol
- MSDS File:
- SDS
| Melting point | 276-278 °C (decomp) |
|---|---|
| Boiling point | 520.8±30.0 °C(Predicted) |
| Density | 1.632±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 3.38±0.30(Predicted) |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C9H6N2O4/c12-9(13)7-4-10-8-2-1-5(11(14)15)3-6(7)8/h1-4,10H,(H,12,13) |
| InChIKey | OOOJXNVTVWRZMA-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C([N+]([O-])=O)C=C2)C(C(O)=O)=C1 |
| CAS DataBase Reference | 6958-37-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
5-Nitroindole-3-carboxylic acid price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 207979 | 5-Nitroindole-3-carboxylic acid | 6958-37-8 | 1.00g | $216 | 2026-05-18 | Buy |
| Matrix Scientific | 207979 | 5-Nitroindole-3-carboxylic acid | 6958-37-8 | 5.00g | $896 | 2026-05-18 | Buy |
| Synthonix | N24944 | 5-Nitro-1H-indole-3-carboxylic acid 97% | 6958-37-8 | 100mg | $37 | 2026-05-06 | Buy |
| Synthonix | N24944 | 5-Nitro-1H-indole-3-carboxylic acid 97% | 6958-37-8 | 250mg | $41 | 2026-05-06 | Buy |
| Synthonix | N24944 | 5-Nitro-1H-indole-3-carboxylic acid 97% | 6958-37-8 | 1g | $43 | 2026-05-06 | Buy |
5-Nitroindole-3-carboxylic acid Chemical Properties, Uses, Production
Synthesis Reference(s)
Journal of Medicinal Chemistry, 35, p. 1019, 1992 DOI: 10.1021/jm00084a007
Synthesis
101832-10-4
6958-37-8
1-(5-nitro-3-indolyl)-2,2,2-trifluoroethanone (7 g, 24.7 mmol) was used as the raw material, which was dissolved in 40% aqueous NaOH solution (40 mL), and the reaction was stirred for 3 hours at 60 °C. After completion of the reaction, the reaction mixture was cooled to 0 °C and acidified by slowly adding 1N HCl aqueous solution to adjust the pH to ~3. Subsequently, the precipitate was collected by filtration, the filter cake was washed with water, and finally the target product 5-nitroindole-3-carboxylic acid (5.9 g, 100% yield) was obtained by concentration as a brown solid. The product was detected by LC/MS (ESI), m/z: 207 [M + 1]+.
References
[1] Patent: WO2017/35351, 2017, A1. Location in patent: Paragraph 0584; 0585; 0586
[2] Russian Journal of General Chemistry, 2017, vol. 87, # 12, p. 3006 - 3016
5-Nitroindole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6744 | 52 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4875 | 55 |
View Latest Price from 5-Nitroindole-3-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 5-nitro-1H-indole-3-carboxylic acid
6958-37-8
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 5-nitro-1H-indole-3-carboxylic acid
6958-37-8
- $3.00
- 98%
- Career Henan Chemical Co
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