3-Cyano-5-nitroindole
- CAS No.
- 7147-14-0
- Chemical Name:
- 3-Cyano-5-nitroindole
- Synonyms
- 3-Cyano-5-nitroindole;5-Nitroindole-3-carbonitrile;1H-Indole-3-carbonitrile, 5-nitro-
- CBNumber:
- CB1664719
- Molecular Formula:
- C9H5N3O2
- Molecular Weight:
- 187.15
- MDL Number:
- MFCD02090219
- MOL File:
- 7147-14-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
3-Cyano-5-nitroindole price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 126673 | 5-Nitro-1H-indole-3-carbonitrile | 7147-14-0 | 1.00g | $684 | 2026-05-18 | Buy |
| Synthonix | N50701 | 5-Nitro-1H-indole-3-carbonitrile 97% | 7147-14-0 | 100mg | $43 | 2026-05-06 | Buy |
| Synthonix | N50701 | 5-Nitro-1H-indole-3-carbonitrile 97% | 7147-14-0 | 250mg | $48 | 2026-05-06 | Buy |
| Synthonix | N50701 | 5-Nitro-1H-indole-3-carbonitrile 97% | 7147-14-0 | 1g | $50 | 2026-05-06 | Buy |
| Synthonix | N50701 | 5-Nitro-1H-indole-3-carbonitrile 97% | 7147-14-0 | 5g | $230 | 2026-05-06 | Buy |
3-Cyano-5-nitroindole Chemical Properties, Uses, Production
Uses
3-Cyano-5-nitroindole is mainly used in pharmaceutical synthesis and organic experiments.
Synthesis
6146-52-7
140-29-4
7147-14-0
GENERAL METHOD: A mixture of CuI (0.6 mmol), 5-nitroindole (0.5 mmol), and phenylacetonitrile (0.6 mmol) in DMF (3.0 mL) was placed in air and reacted with stirring for 34 h at 100 °C, followed by cooling to room temperature. Upon completion of the reaction, the reaction mixture was quenched with 10 mL of water followed by extraction with dichloromethane (DCM, 3 x 10 mL). The organic layers were combined, washed with saturated aqueous sodium chloride solution and dried with anhydrous magnesium sulfate (MgSO). Finally, the solution was concentrated under reduced pressure and purified by column chromatography to afford the target product 5-nitroindole-3-carbonitrile.
References
[1] Tetrahedron, 2013, vol. 69, # 21, p. 4236 - 4240
3-Cyano-5-nitroindole Preparation Products And Raw materials
Raw materials
Preparation Products
3-Cyano-5-nitroindole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3997 | 55 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2277 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. | 02161555100 | China | 820 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai CR Corporation Limited | 13917420128 13062833949 | fred.wen@crcorporation.cn | China | 9776 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
