Methyl 2-methoxy-5-sulfamoylbenzoate
- CAS No.
- 33045-52-2
- Chemical Name:
- Methyl 2-methoxy-5-sulfamoylbenzoate
- Synonyms
- Sulpride Impurity B;Methyl2-Methoxy-5-S;Sulpiride EP Impurity B;Sulpiride Impurity B(EP);Sulpiride impurity B CRS;2-Methoxy-5-sulfamoylbenzoic;methyl 5-sulphamoyl-o-anisate;Sulpiride impurity B (S2192000);Methyl[5-Amino Sulfonyl-2-Methoxy];Methyl 2-Methoxy-5-sulphamoylbenzoa
- CBNumber:
- CB9455786
- Molecular Formula:
- C9H11NO5S
- Molecular Weight:
- 245.25
- MDL Number:
- MFCD01317542
- MOL File:
- 33045-52-2.mol
- MSDS File:
- SDS
| Melting point | 175-177 °C (lit.) |
|---|---|
| Boiling point | 439.8±55.0 °C(Predicted) |
| Density | 1.360±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.94±0.60(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C9H11NO5S/c1-14-8-4-3-6(16(10,12)13)5-7(8)9(11)15-2/h3-5H,1-2H3,(H2,10,12,13) |
| InChIKey | MKDYDRQLKPGNNU-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC(S(N)(=O)=O)=CC=C1OC |
| LogP | 0.36 |
| CAS DataBase Reference | 33045-52-2(CAS DataBase Reference) |
| FDA UNII | F8XVA6KYT6 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xi |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 2922500090 |
| Storage Class | 11 - Combustible Solids |
| REACH Registrations | Active |
Methyl 2-methoxy-5-sulfamoylbenzoate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S2192000 | Sulpiride impurity B European Pharmacopoeia (EP) Reference Standard | 33045-52-2 | 10 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | 522279 | Methyl 2-methoxy-5-sulfamoylbenzoate 98% | 33045-52-2 | 25g | $168 | 2026-04-30 | Buy |
| Sigma-Aldrich | S2192000 | Sulpiride impurity B European Pharmacopoeia (EP) Reference Standard | 33045-52-2 | s2192000 | $153 | 2024-03-01 | Buy |
| TCI Chemical | M1942 | Methyl 5-(Aminosulfonyl)-2-methoxybenzoate >98.0%(HPLC) | 33045-52-2 | 25g | $80 | 2021-12-16 | Buy |
| Biosynth | IA145486 | 5-(Aminosulfonyl)-2-methoxy-benzoic acid methyl ester | 33045-52-2 | 0.25g | $250 | 2026-06-04 | Buy |
Methyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties, Uses, Production
Uses
Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents.
Preparation
Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.
synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate
General Description
Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate.
Methyl 2-methoxy-5-sulfamoylbenzoate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SUZHOU AUSUN CHEMICAL CO., LTD. | 0512-68244182 15850237342 | ausunjoy@163.com | China | 29 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Beijing Isomersyn Technology CO;LTD | 010-82954736 13391601435 | sales@isomersyn.com | China | 3294 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Latest Price from Methyl 2-methoxy-5-sulfamoylbenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-06-30 | Methyl 2-methoxy-5-sulfamoylbenzoate
33045-52-2
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2026-03-20 | Methyl 2-methoxy-5-sulfamoylbenzoate
33045-52-2
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2023-09-07 | Methyl 2-methoxy-5-sulfamoylbenzoate
33045-52-2
|
$100.00 | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD |
-

- Methyl 2-methoxy-5-sulfamoylbenzoate
33045-52-2
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- Methyl 2-methoxy-5-sulfamoylbenzoate
33045-52-2
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Methyl 2-methoxy-5-sulfamoylbenzoate
33045-52-2
- $100.00
- 99
- Hebei Fengqiang Trading Co., LTD
33045-52-2 (Methyl 2-methoxy-5-sulfamoylbenzoate) Related Search:
1of4





