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BSc5371

BSc5371 Structure
BSc5371 structure
CAS No.
2286419-03-0
Chemical Name:
BSc5371
Synonyms
BSc5371;BSc-5371,BSc5371;1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[(Z)-[5-[(ethenylsulfonyl)amino]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-
CBNumber:
CB95540580
Molecular Formula:
C24H31N5O4S
Molecular Weight:
485.6
MDL Number:
MFCD31813808
MOL File:
2286419-03-0.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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BSc5371 Properties

Density 1.305±0.06 g/cm3(Predicted)
pka 8.15±0.20(Predicted)

BSc5371 Chemical Properties, Uses, Production

Uses

BSc5371 is a potent and irreversible FLT3 inhibitor, with Kds of 1.3, 0.83, 1.5, 5.8 and 2.3 nM for mutant FLT3(D835H), FLT3(ITD, D835V), FLT3(ITD, F691L), FLT3-ITD and wild type FLT3wt, respectively. BSc5371 is cytotoxic to FLT3-dependent cell lines[1].

References

[1] Bensinger D, et al. Virtual Screening Identifies Irreversible FMS-like Tyrosine Kinase 3 Inhibitors with Activity toward Resistance-Conferring Mutations. J Med Chem. 2019 Mar 14;62(5):2428-2446. DOI:10.1021/acs.jmedchem.8b01714

BSc5371 Preparation Products And Raw materials

Raw materials

Preparation Products

BSc5371 Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
BOC Sciences 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from BSc5371 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BSc5371 pictures 2026-07-27 BSc5371
2286419-03-0
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
BSc5371 pictures 2026-07-27 BSc5371
2286419-03-0
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
BSc5371 pictures 2025-08-22 BSc5371
2286419-03-0
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • BSc5371 pictures
  • BSc5371
    2286419-03-0
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
  • BSc5371 pictures
  • BSc5371
    2286419-03-0
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
  • BSc5371 pictures
  • BSc5371
    2286419-03-0
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

2286419-03-0 (BSc5371) Related Search:

FLT3 Protein, HUMAN (T227M, HEK293, HIS) AT9283 LDC1267 Sitravatinib Dovitinib
FLT3 Protein, Human (HEK293, hFc)

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BSc5371 BSc-5371,BSc5371 1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[(Z)-[5-[(ethenylsulfonyl)amino]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl- 2286419-03-0