Cleaved Caspase-3 (Asp175) Antibody

CAS No.
Chemical Name:
Cleaved Caspase-3 (Asp175) Antibody
Synonyms
Cleaved Caspase-3 (Asp175) Antibody
CBNumber:
CB95618056
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Cleaved Caspase-3 (Asp175) Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly polymerase. Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position.

References

[1] Fernandes-Alnemri, T. et al. (1994) J Biol Chem 269, 30761-4.
[2] Nicholson, D.W. et al. (1995) Nature 376, 37-43.

Cleaved Caspase-3 (Asp175) Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Cleaved Caspase-3 (Asp175) Antibody