7-Aminoactinomycin D
- CAS No.
- 7240-37-1
- Chemical Name:
- 7-Aminoactinomycin D
- Synonyms
- 7-AAD;7-ADD;7-AMINO-AMD;7-AAD (FIR);7-AAD/CH85402;7-ACTINOMYCIN C;7-AMINOACTINOMYCIN;7-AMINODACTINOMYCIN;7-Aminoactinomycin D;7-AMINOACTINOMYCIN C1
- CBNumber:
- CB7145520
- Molecular Formula:
- C62H87N13O16
- Molecular Weight:
- 1270.43
- MDL Number:
- MFCD00077295
- MOL File:
- 7240-37-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 252~253℃ |
|---|---|
| Boiling point | 1400.8±65.0 °C(Predicted) |
| Density | 1.44 |
| Flash point | 801℃ |
| storage temp. | -20°C |
| solubility | chloroform: 1 mg/mL, clear, red |
| form | powder |
| pka | 8.90±0.70(Predicted) |
| color | red to dark purple |
| Appearance | purple powder |
| BRN | 5915844 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions should be made fresh daily. |
| InChIKey | YXHLJMWYDTXDHS-UHFFFAOYSA-N |
| FDA UNII | DXS32PH95R |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T+,T | |||||||||
| Risk Statements | 26/27/28-36/37/38 | |||||||||
| Safety Statements | 26-28-36/37-45 | |||||||||
| RIDADR | UN 3462 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AU1579000 | |||||||||
| F | 8-10-21 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29419090 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Oral | |||||||||
| NFPA 704 |
|
7-Aminoactinomycin D price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A9400 | 7-Aminoactinomycin D ~97% (HPLC), powder | 7240-37-1 | 1mg | $219 | 2026-04-30 | Buy |
| Sigma-Aldrich | 129935 | Actinomycin D, 7-Amino- | 7240-37-1 | 1mg | $173.9 | 2021-12-16 | Buy |
| Cayman Chemical | 11397 | 7-Aminoactinomycin D ≥95% | 7240-37-1 | 1mg | $121 | 2026-04-30 | Buy |
| Cayman Chemical | 11397 | 7-Aminoactinomycin D ≥95% | 7240-37-1 | 5mg | $477 | 2026-04-30 | Buy |
| Biosynth | FA146843 | 7-Aminoactinomycin D | 7240-37-1 | 1mg | $268.37 | 2026-06-04 | Buy |
7-Aminoactinomycin D Chemical Properties, Uses, Production
Description
7-Aminoactinomycin D (7-AAD) is a fluorescent DNA dye that is commonly used for the detection or exclusion of non-viable cells in flow cytometric analysis, as it is generally excluded by live cells. It displays excitation spectra of 488, 546, and 578 nm and an emission spectrum of 650 nm. As 7-AAD is detected in the far red range of the spectrum, it exhibits minimal spectral overlap with commonly used probes, therefore it can be used in conjunction with probes such as FITC. 7-AAD has been used to evaluate apoptosis and cell-mediated cytotoxicity and to stain DNA in cells that have been fixed and permeabilized by a variety of methods.
Chemical Properties
Purple powder
Uses
Fluorescent DNA stain. A featured product for Apoptosis research.
Uses
7-Aminoactinomycin D is a fluorescent DNA dye for apoptosis and flow cytomtery studies.
Definition
ChEBI: 7-aminoactinomycin D is a chromopeptide. It has a role as a fluorochrome.
General Description
Free form:
Excitation: 503 nm (0.01 M phosphate buffer, pH 7.0 containing 0.1 mM EDTA); 550 nm
Emission: 675 nm (0.01 M phosphate buffer, pH 7.0 containing 0.1 mM EDTA); 672 nm
DNA Complex:
Excitation: 543 nm; 555 nm
Emission: 655 nm; 665 nm
Biochem/physiol Actions
Primary Targetleukemias and sarcomas
storage
Store at -20°C
References
[1] TANJA TELIEPS. Cellular-FLIP, Raji isoform (c-FLIPR) modulates cell death induction upon T-cell activation and infection[J]. European Journal of Immunology, 2013, 43 6: 1499-1510. DOI:10.1002/eji.201242819
[2] INGRID SCHMID Beth D J Christel Uittenbogaart. Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D[J]. Nature Protocols, 2007, 2 1: 187-190. DOI:10.1038/nprot.2006.458
[3] K TOBA. Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY.[J]. European Journal of Haematology, 2000, 64 1: 10-21. DOI:10.1034/j.1600-0609.2000.09005.x
[4] HERVÉ LECOEUR. Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods[J]. Journal of immunological methods, 1997, 209 2: Pages 111-123. DOI:10.1016/s0022-1759(97)00138-5
[5] X SU. Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect.[J]. Journal of immunology, 1996, 156 11: 4198-4208.
Abs/Em Maxima
527 (complex)/640 (complex) nm
7-Aminoactinomycin D Preparation Products And Raw materials
Raw materials
Preparation Products
7-Aminoactinomycin D Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| MO-CHEM | 13851755987 | dingdalei@mo-chem.com.cn | China | 206 | 58 |
| Huai Hua Binfengchem Co., Ltd | 0745-2866851 17711757908 | 3907837691@qq.com | China | 4745 | 58 |
| Suzhou UELandy Biotechnology Co., Ltd. | 18094275008 | tanxueliang@bioscience.com.cn | China | 487 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Nanjing Asian Chemical Co., Ltd. | +86 (25) 82263158 | China | 262 | 60 | |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
View Latest Price from 7-Aminoactinomycin D manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | 7-Aminoactinomycin D
7240-37-1
|
$275.00-1080.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2019-12-31 | 7-AMINOACTINOMYCIN D
7240-37-1
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- 7-Aminoactinomycin D
7240-37-1
- $275.00-1080.00
- TargetMol Chemicals Inc.
-
- 7-AMINOACTINOMYCIN D
7240-37-1
- $1.00
- 95-99%
- Career Henan Chemical Co
