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1-(2-Methoxyphenyl)piperazine

1-(2-Methoxyphenyl)piperazine structure

CAS No.: 35386-24-4

Chemical Name:: 1-(2-Methoxyphenyl)piperazine

Synonyms: 2-MPP;D 15157;AKOS BBS-00003584;Uradil impurity 18;Urapidil Impurity 6;TIMTEC-BB SBB003620;RARECHEM AH CK 0126;2-Piperazinoanisole;LABOTEST-BB LT00233095;1-(o-Anisyl)piperazine

CBNumber:: CB9669765

Molecular Formula:: C11H16N2O

Molecular Weight:: 192.26

MDL Number:: MFCD00005958

MOL File:: 35386-24-4.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
1-(2-Methoxyphenyl)piperazine 98%	M22601	5g	$45.4
1-(2-Methoxyphenyl)piperazine 98%	M22601	25g	$107
1-(2-Methoxyphenyl)piperazine >98.0%(GC)(T)	M0883	5g	$33
1-(2-Methoxyphenyl)piperazine >98.0%(GC)(T)	M0883	25g	$84
1-(2-Methoxyphenyl)piperazine	M266220	25g	$120
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1-(2-Methoxyphenyl)piperazine Properties

Melting point	35-40 °C (lit.)
Boiling point	130-133 °C/0.1 mmHg (lit.)
Density	1.095 g/mL at 25 °C (lit.)
refractive index	n20/D 1.575(lit.)
Flash point	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Liquid After Melting
pka	8.98±0.10(Predicted)
color	Clear colorless to yellow
Water Solubility	Soluble in chloroform, ethyl acetate, and methanol. Insoluble in water
Sensitive	Air Sensitive
BRN	167888
InChI	InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChIKey	VNZLQLYBRIOLFZ-UHFFFAOYSA-N
SMILES	N1(C2=CC=CC=C2OC)CCNCC1
LogP	1.67
CAS DataBase Reference	35386-24-4(CAS DataBase Reference)
FDA UNII	81NJO1330A
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Hazard Codes

C,Xi

Risk Statements

34-36/37/38

Safety Statements

26-36/37/39-45-28A-36

RIDADR

UN 3263 8/PG 3

WGK Germany

3-10

Hazard Note

Irritant

HazardClass

PackingGroup

Ⅲ

HS Code

29349990

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
2		0

1-(2-Methoxyphenyl)piperazine price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M22601	1-(2-Methoxyphenyl)piperazine 98%	35386-24-4	5g	$45.4	2025-07-31	Buy
Sigma-Aldrich	M22601	1-(2-Methoxyphenyl)piperazine 98%	35386-24-4	25g	$107	2025-07-31	Buy
TCI Chemical	M0883	1-(2-Methoxyphenyl)piperazine >98.0%(GC)(T)	35386-24-4	5g	$33	2025-07-31	Buy
TCI Chemical	M0883	1-(2-Methoxyphenyl)piperazine >98.0%(GC)(T)	35386-24-4	25g	$84	2025-07-31	Buy
TRC	M266220	1-(2-Methoxyphenyl)piperazine	35386-24-4	25g	$120	2021-12-16	Buy

Product number	Packaging	Price	Buy
M22601	5g	$45.4	Buy
M22601	25g	$107	Buy
M0883	5g	$33	Buy
M0883	25g	$84	Buy
M266220	25g	$120	Buy

1-(2-Methoxyphenyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellow liquid after melting

Uses

A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).

Uses

It is used as pharmaceutical intermediate. N-alkylated 1-(2-methyoxyphenyl)piperazines markedly improved affinity and selectivity of the dopamine D3 receptor which is recognized as a potential therapeutic target for the treatment of various neurological and psychiatric disorders.

Uses

1-(2-Methoxyphenyl)piperazine can be used:

To functionalize pyrazolylvinyl ketones via Aza-Michael addition reaction.
To prepare cyclic amine substituted Tr?ger′s base derivatives.
To prepare functionalized bis(mercaptoimidazolyl)borates by reacting with the activated ester, [(1-methyl-2-mercaptoimidazol-5-yl)carbonyl]succinimide.

Definition

ChEBI: 1-(2-methoxyphenyl)piperazine is a member of piperazines.

1-(2-Methoxyphenyl)piperazine Preparation Products And Raw materials

Raw materials

Silica gel o-Anisidine Hexane Benzyltriethylammonium chloride 2-Diethylaminoethylchloride hydrochloride

Ethyl acetate Sodium carbonate

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Preparation Products

CYCLOHEXANECARBOXAMIDE, N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-, HYDROCHLORIDE (1:3) 1-(2-HYDROXYPHENYL)PIPERAZINE 1-(2-METHOXY-5-NITROPHENYL)PIPERAZINE 1-(2-HYDROXYPHENYL)PIPERAZINE DIHYDROBROMIDE 5,6,7,8-tetrahydro-2-[4-(2-methoxyphenyl)-1-piperazinyl]-4(3H)-Quinazolinone

1-(2-Methoxyphenyl)piperazine hydrobromide

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1-(2-Methoxyphenyl)piperazine Suppliers

Global( 338)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28387	80
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9297	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58

Supplier	Advantage
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
Henan Aochuang Chemical Co.,Ltd.	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
HubeiwidelychemicaltechnologyCo.,Ltd	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 1-(2-Methoxyphenyl)piperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-07-25	1-(2-Methoxyphenyl)piperazine 35386-24-4	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-04-04	1-(2-Methoxyphenyl)piperazine 35386-24-4	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2025-04-04	AochuangChem-1-(2-Methoxyphenyl)piperazine 35386-24-4	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.

1-(2-Methoxyphenyl)piperazine
35386-24-4
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

1-(2-Methoxyphenyl)piperazine
35386-24-4
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

AochuangChem-1-(2-Methoxyphenyl)piperazine
35386-24-4
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

1-(2-Methoxyphenyl)piperazine Spectrum

1-(2-Methoxyphenyl)piperazine(35386-24-4)MS 1-(2-Methoxyphenyl)piperazine(35386-24-4)¹HNMR 1-(2-Methoxyphenyl)piperazine(35386-24-4)¹³CNMR 1-(2-Methoxyphenyl)piperazine(35386-24-4)IR1 1-(2-Methoxyphenyl)piperazine(35386-24-4)IR2 1-(2-Methoxyphenyl)piperazine(35386-24-4)IR3 1-(2-Methoxyphenyl)piperazine(35386-24-4)Raman

35386-24-4(1-(2-Methoxyphenyl)piperazine)Related Search:

6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil 2-Methylpiperazine Piperazine N-Aminoethylpiperazine Piperacillin

2-Ethylhexyl ferulate 1-(3-AMinopropyl)-4-(2-Methoxyphenyl)piperazine 97% 4-(3-Hydroxypropylamino)-1,3-dimethyluracil O-DesMethyl Urapidil 6-[(3-chloropropyl)amino]-1,3-dimethyluracil

2-Demethoxy-2-chloro urapidil Urapidil impurity 7 1,3-Dimethylbarbituric acid 2-Demethoxy-4-methoxy urapidil 3-[4-(2-methoxyphenyl)-1-piperazinyl]propanenitrile

6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione 1-(4-Methoxyphenyl)piperazine Propiophenone

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RARECHEM AH CK 0126 TIMTEC-BB SBB003620 Urapidil Impurity 6 LABOTEST-BB LT00233095 AKOS BBS-00003584 1-(2-METHOXYLPHENYL)-PIPERAZINE 2-(PIPERAZIN-1-YL)METHOXYBENZENE 2-(1-PIPERAZINYL)ANISOLE 1-(O-METHOXYPHENYL)PIPERAZINE 1-(2-Methoxyphenyl)piperazine,98% 1-(2-Methoxyphenyl)piperazine 97% 1-(2-methoxyphenylj-piperazine 1-(2-METHOXYPHENYL) PIPERAZINE BASE ( OMEPPBA ) Piperazine, 1-(2-methoxyphenyl)- 2-MPP 2-Piperazinoanisole 1-(2-Methoxyphenyl)piperazine 1-(o-Anisyl)piperazine 1-[2-(Methyloxy)phenyl]piperazine D 15157 N-(2-Methoxyphenyl)piperazine N-(o-Methoxyphenyl)piperazine 1-(2-Methoxypheny)piperazine 1-(2-Methoxyphenyl)piperazine, 98+% 5GR 1-(2-Methoxyphenyl)piperazine> TIANFU-CHEM 35386-24-4 1-(2-Methoxyphenyl)piperazine dihydrogen 1-(2-methoxyphenyl)piperazine dichloride AochuangChem-1-(2-Methoxyphenyl)piperazine 1-(2-Methoxyphenyl)piperazine, ≥ 98.0% Uradil impurity 18 Posaconazole Impurity 223 35386-24-4 35386-24-47 36386-24-4 C11H16N2O Building Blocks Heterocyclic Building Blocks Piperazines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Bioactive Small Molecules C11 Cell Biology Chemical Synthesis API intermediates (intermediate of urapidil) Building Blocks Heterocyclic Building Blocks Piperazines Piperidines, Piperidones, Piperazines BUILDING BLOCKS Piperaizine Heterocyclic Building Blocks M