ChemicalBook >> CAS DataBase List >>2-Methylpiperazine

2-Methylpiperazine

2-Methylpiperazine structure

CAS No.: 109-07-9

Chemical Name:: 2-Methylpiperazine

Synonyms: MP;2MPRZ;2-methyl-piperazin;2-METHYLPIPERAZINE;Piperazine,2-methyl-;2-Methylpiperazine>2-Methylpiperazine,98%;2-Methylpiperazine ,99%;2-Methylpiperazine, 97+%;(+/-)-2-METHYLPIPERAZINE

CBNumber:: CB5376580

Molecular Formula:: C5H12N2

Molecular Weight:: 100.16

MDL Number:: MFCD00005954

MOL File:: 109-07-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:10:45

Request For Quotation

2-Methylpiperazine Properties

Melting point	61-63 °C (lit.)
Boiling point	155 °C/763 mmHg (lit.)
Density	0.817 g/cm
refractive index	1.4378 (estimate)
Flash point	149 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	435g/l
pka	pK1:5.62(+2);pK2:9.60(+1) (25°C)
form	Crystalline Powder, Crystals and/or Chunks
color	White to yellow
PH	11-12 (50g/l, H2O)
Water Solubility	78 g/100 mL (25 ºC)
Sensitive	Air Sensitive & Hygroscopic
BRN	383566
Henry's Law Constant	5.0×10³ mol/(m³Pa) at 25℃, Nguyen (2013)
InChI	1S/C5H12N2/c1-5-4-6-2-3-7-5/h5-7H,2-4H2,1H3
InChIKey	JOMNTHCQHJPVAZ-UHFFFAOYSA-N
SMILES	CC1CNCCN1
CAS DataBase Reference	109-07-9(CAS DataBase Reference)
FDA UNII	D0LWN1061P
NIST Chemistry Reference	Piperazine, 2-methyl-(109-07-9)
EPA Substance Registry System	Piperazine, 2-methyl- (109-07-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05

Signal word

Danger

Hazard statements

H228-H314

Precautionary statements

P210-P240-P260-P280-P303+P361+P353-P305+P351+P338

PPE

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes

F,Xi

Risk Statements

11-36/37/38

Safety Statements

16-26-36/37/39-36

RIDADR

UN 1325 4.1/PG 2

WGK Germany

RTECS

TM1225020

TSCA

TSCA listed

HazardClass

4.1

PackingGroup

III

HS Code

29339900

Storage Class

4.1B - Flammable solid hazardous materials

Hazard Classifications

Eye Dam. 1
Flam. Sol. 1
Skin Corr. 1B

REACH Registrations

Active

Limited Quantities

1.0 Kg (2.2 lbs)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	2
2		0

2-Methylpiperazine price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M72404	2-Methylpiperazine 95%	109-07-9	100g	$116	2026-04-30	Buy
TCI Chemical	M1179	2-Methylpiperazine >99.0%(GC)	109-07-9	25g	$37	2026-04-30	Buy
TCI Chemical	M1179	2-Methylpiperazine >99.0%(GC)	109-07-9	500g	$296	2026-04-30	Buy
Usbiological	283436	2-Methylpiperazine Asreported	109-07-9	100g	$436	2026-06-03	Buy
Usbiological	283436	2-Methylpiperazine Asreported	109-07-9	250g	$669	2026-06-03	Buy

Product number	Packaging	Price	Buy
M72404	100g	$116	Buy
M1179	25g	$37	Buy
M1179	500g	$296	Buy
283436	100g	$436	Buy
283436	250g	$669	Buy

2-Methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

white to yellow crystalline powder and chunks

Uses

2-Methylpiperazine is used as a reagent in the design, synthesis and biological evaluation of diaminoquinazolines as b-catenine/Tcell transcription factor 4 (Tcf4) pathway inhibitor.

Purification Methods

Purify it by zone melting and by distillation. It is hygroscopic. The picrate has m 275-276o. [Beilstein 23 II 16, 23 III/IV 393, 23/3 V 267.]

2-Methylpiperazine synthesis

Synthesis of 2-Methylpiperazine from 3-Methyl-1-benzyl-piperazine

2-Methylpiperazine Preparation Products And Raw materials

Raw materials

Ethylenediamine Propylene oxide 3-Methyl-1-benzyl-piperazine 2,5-Dimethylpiperazine 2,6-Dimethylpiperazine

D(+)-Glucose

1of2

Preparation Products

2-Methylpyrazine Lomefloxacin TEMAFLOXACIN 1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-quino line-3-carboxylic acid Lomefloxacin hydrochloride

4-N-Boc-2-Methyl-piperazine (R)-(-)-2-Methylpiperazine DL-Alaninol 1,2-Dimethyl-piperazine Piperazine

1of2

2-Methylpiperazine Suppliers

Global( 478)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Jiahua Herong Biotechnology Co., Ltd	18916155073	market@trustwe.com	China	203	58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.	13396369453 18678026865	sdfantai@163.com	China	904	58
Weifang Mingran Chemical Co., Ltd.	QQ117761326 QQ2829453795 15063661899;	mingranchem@163.com	China	493	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Beijing dtftchem Technology Co., Ltd.	010-60275820 13031183356	elainezt@sina.com	China	1386	62
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61

Supplier	Advantage
Shanghai Jiahua Herong Biotechnology Co., Ltd	58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.	58
Weifang Mingran Chemical Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
ShangHai DEMO Chemical Co.,Ltd	57
Beijing dtftchem Technology Co., Ltd.	62
Energy Chemical	61

2-Methylpiperazine: Key Cyclic Diamine Building Block
2-Methylpiperazine is a key chiral diamine building block for CCR5 anti-HIV drugs and high-performance CO2 capture solvent ble....
Apr 15,2026

View Lastest Price from 2-Methylpiperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-14	2-Methylpiperazine 109-07-9	$5.00	1kg	≥99%	200mt/year	Jinan Finer Chemical Co., Ltd
2026-05-28	2-Methylpiperazine 109-07-9	$9.00	1KG	99.9	1 ton	Hebei Chuanghai Biotechnology Co,.LTD
2026-03-20	2-Methylpiperazine 109-07-9	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

2-Methylpiperazine
109-07-9
$5.00
≥99%
Jinan Finer Chemical Co., Ltd

2-Methylpiperazine
109-07-9
$9.00
99.9
Hebei Chuanghai Biotechnology Co,.LTD

2-Methylpiperazine
109-07-9
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Methylpiperazine Spectrum

2-Methylpiperazine(109-07-9)MS 2-Methylpiperazine(109-07-9)¹HNMR 2-Methylpiperazine(109-07-9)¹³CNMR 2-Methylpiperazine(109-07-9)IR1 2-Methylpiperazine(109-07-9)Raman

109-07-9(2-Methylpiperazine)Related Search:

Levodropropizine N-Aminoethylpiperazine Piperazine 2-Ethylhexyl ferulate Piperacillin

1,2-Dimethylhydrazine Dihydrochloride 1-METHYLPIPERAZINE 2,5-Dimethylpiperazine 2,6-Dimethylpiperazine Mianserin hydrochloride

Dihydroergotamine tartrate 1-Methylpiperazine dihydrochloride Ethyl 2-(3-oxo-2-piperazinyl)acetate DL-2-Aminopropionic anhydride Piperazine-2-carboxylic acid

2-Bromomethyl-1,4-benzodioxane 1,2,4-Trimethyldiethylenediamine 4,4'-Difluorobenzhydrylpiperazine

1of4

2-methyl-piperazin 2-METHYLDIETHYLENEDIAMINE (+/-)-2-METHYLPIPERAZINE 2-METHYLPIPERAZINE 2MPRZ 2-METHYLPIPERAZINE/LOMEFLOXCIN 2-Methylpiperazine ,99% 2-Methylpiperazine,98% 2-Methylpiperazine, 98% 100GR 2-Methylpiperazine, 97+% Piperazine,2-methyl- (2R)-2-methylpiperazinediium 2-Methylpiperazine> 2-Methylpiperazine ISO 9001：2015 REACH TIANFUCHEM--High purity 109-07-9 2-Methylpiperazine MP 2-Methylpiperazine (base) 109-07-9 Building Blocks Heterocyclic Building Blocks Piperazines Building Blocks C4 to C8 Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Piperidines, Piperidones, Piperazines Piperaizine Piperazine derivates Piperazines OLED