3-Pyridineacrylic acid
- CAS No.
- 1126-74-5
- Chemical Name:
- 3-Pyridineacrylic acid
- Synonyms
- 3-(3-PYRIDYL)ACRYLIC ACID;Pyridine-3-acrylic acid;AKOS AUF2066;RARECHEM BK HC S246;3-Pyridineacrylicaci;3-PYRIDYLACRYLIC ACID;3-PYRIDINEACRYLIC ACID;3-Pyridylpropionic acid;3-PYRIDINYL-ACRYLIC ACID;B-(3-PYRIDYL)ACRYLIC ACID
- CBNumber:
- CB9699461
- Molecular Formula:
- C8H7NO2
- Molecular Weight:
- 149.15
- MDL Number:
- MFCD00006410
- MOL File:
- 1126-74-5.mol
- MSDS File:
- SDS
| Melting point | 232-235 °C (dec.)(lit.) |
|---|---|
| Boiling point | 270.21°C (rough estimate) |
| Density | 1.2517 (rough estimate) |
| refractive index | 1.5320 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 3.13±0.10(Predicted) |
| form | Solid |
| color | White |
| InChI | InChI=1S/C8H7NO2/c10-8(11)4-3-7-2-1-5-9-6-7/h1-6H,(H,10,11) |
| InChIKey | VUVORVXMOLQFMO-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C=CC1=CC=CN=C1 |
| CAS DataBase Reference | 1126-74-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36-37/39-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
3-Pyridineacrylic acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P1157 | 3-(3-Pyridyl)acrylic Acid >98.0%(T) | 1126-74-5 | 5g | $27 | 2026-04-30 | Buy |
| TCI Chemical | P1157 | 3-(3-Pyridyl)acrylic Acid >98.0%(T) | 1126-74-5 | 25g | $90 | 2026-04-30 | Buy |
| TRC | TRC-P991285-50MG | 3-Pyridineacrylic Acid | 1126-74-5 | 50mg | $72 | 2026-06-03 | Buy |
| TRC | TRC-P991285-2.5G | 3-Pyridineacrylic Acid | 1126-74-5 | 2.5g | $154 | 2026-06-03 | Buy |
| TRC | TRC-P991285-10G | 3-Pyridineacrylic Acid | 1126-74-5 | 10g | $246 | 2026-06-03 | Buy |
3-Pyridineacrylic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
3-Pyridineacrylic Acid is an inhibitor of peptidylglycine amidating monooxygenase.
Synthesis
100390-47-4
19337-97-4
To a solution of butyl 3-(pyridin-3-yl)prop-2-enoate (70 g, 341 mmol, 1.00 equiv) in ethanol (150 mL) was added a solution of potassium hydroxide (40 g, 712.94 mmol, 2.09 equiv) in water (150 mL). The reaction mixture was stirred at room temperature for 20 hours. Upon completion of the reaction, the pH of the solution was adjusted to 6 with 12 M hydrochloric acid.The precipitate was collected by filtration to give 50 g (98% yield) of trans-3-(3-pyridyl)acrylic acid as an off-white solid.LCMS analysis (Method C, electrospray ionization, m/z): retention time = 0.78 min, m/z = 149.9 [M+H]+.
References
[1] Patent: WO2014/74715, 2014, A1. Location in patent: Paragraph 0170
[2] Journal of Medicinal Chemistry, 2014, vol. 57, # 3, p. 770 - 792
3-Pyridineacrylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEWOO PHARMATECH (SHANGHAI) CO.,LTD | 15800805830 | miao@lewoopharma.com.cn | China | 994 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Lastest Price from 3-Pyridineacrylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-13 | 3-Pyridineacrylic acid
1126-74-5
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2025-12-24 | 3-Pyridineacrylic acid
1126-74-5
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-01-13 | 3-Pyridineacrylic acid
1126-74-5
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- 3-Pyridineacrylic acid
1126-74-5
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 3-Pyridineacrylic acid
1126-74-5
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-Pyridineacrylic acid
1126-74-5
- $9.80
- ≥98%
- Career Henan Chemical Co
