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α-Chloralose

CAS No.
15879-93-3
Chemical Name:
α-Chloralose
Synonyms
ALPHA-CHLORALOSE;murex;somio;alfamat;aphosal;S-17086;dulcidor;alphakil;krakalos;ALFA-4(R)
CBNumber:
CB9710120
Molecular Formula:
C8H11Cl3O6
Molecular Weight:
309.53
MDL Number:
MFCD00005542
MOL File:
15879-93-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-31 15:25:14

α-Chloralose Properties

Melting point 178-182 °C
alpha 18 º (c=2, 95% C2H5OH)
Boiling point 424.33°C (rough estimate)
Density 1.6066 (rough estimate)
vapor pressure Negligible at room temperature
refractive index 1.5320 (estimate)
solubility ethanol: 10 mg/mL or yellow-brown, clear to slightly hazy, colorless to faintly yellow
pka 12.89±0.60(Predicted)
form Solid
color White to Almost white
optical activity [α]20/D +17±2°, 5 hr, c = 2% in ethanol
Water Solubility 0.44 g/100 mL (15 ºC)
Merck 14,2072
BRN 85418
Stability Stable. Incompatible with strong oxidizing agents.
InChI 1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1
InChIKey OJYGBLRPYBAHRT-IPQSZEQASA-N
SMILES OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl
LogP 1.020
CAS DataBase Reference 15879-93-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 238BZ29MUE
EPA Substance Registry System Chloralose (15879-93-3)
UNSPSC Code 12352201
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Environment (GHS09)
GHS06,GHS09
Signal word  Danger
Hazard statements  H300-H332-H336-H410
Precautionary statements  P501-P261-P273-P270-P271-P264-P391-P301+P310+P330-P304+P340+P312-P403+P233-P405
target organs Central nervous system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  20/22-20/21/22
Safety Statements  16-24/25-28-28A-36
RIDADR  3249
WGK Germany  1
RTECS  FM9450000
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  29400090
Storage Class 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Acute Tox. 4 Inhalation
Aquatic Acute 1
Aquatic Chronic 1
STOT SE 3
Toxicity LD50 orally in mice: 400 mg/kg (Schafer)
NFPA 704
1
3 0

α-Chloralose price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 23120 α-Chloralose ≥98.0% (chloralose, AT) 15879-93-3 100g $70 2025-07-31 Buy
Sigma-Aldrich 23120 α-Chloralose ≥98.0% (chloralose, AT) 15879-93-3 500g $198.8 2025-07-31 Buy
Sigma-Aldrich 23120 α-Chloralose ≥98.0% (chloralose, AT) 15879-93-3 25g $27.8 2023-06-20 Buy
TCI Chemical C0074 alpha-Chloralose (contains beta-isomer) >85.0%(GC) 15879-93-3 25g $60 2026-04-30 Buy
TRC TRC-A576005-5G Chloralose 15879-93-3 5g $101 2026-06-03 Buy
Product number Packaging Price Buy
23120 100g $70 Buy
23120 500g $198.8 Buy
23120 25g $27.8 Buy
C0074 25g $60 Buy
TRC-A576005-5G 5g $101 Buy

α-Chloralose Chemical Properties, Uses, Production

Description

Chloralose, (R)-1,2-O-(2,2,2-trichloroethylidene)- α-D-glucofuranose, is a crystalline powder which is soluble in water, fairly soluble in alcohol, diethyl ether, glacial acetic acid, sparingly soluble in chloroform, practically insoluble in petroleum ether.
Chloralose is produced by reaction of glucose with waterfree chloral under heating (21).

Chemical Properties

needle-like crystals or powder

Uses

Coating seeds to protect them from birds.

Uses

It has been employed widely as an animal anesthetic in the laboratory setting. alpha-chloralose is a true anesthetic or an immobilizing agent with sedative-hypnotic properties has important implications. Canada geese (Branta canadensis) and blue geese (Chen caerulescens) were caught with alpha-chloralose, an oral hypnotic administered on bait. Wild turkeys (Meleagris gallopavo) were captured with alpha-chloralose, an oral anesthetic.

Uses

Chloralose is used for the control of rodents, particularly mice, and as a bird repellent and a bird narcotic.

Production Methods

The commercial production of chloralose involves the condensation of chloral (trichloroacetaldehyde) with glucose under acidic conditions. This reaction forms a glycosidic bond between the aldehyde group of chloral and the hydroxyl groups of glucose, resulting in the formation of chloralose.

Hazard

May cause addiction, highly toxic.

Mechanism of action

Acts via the depression of the central nervous system, primarily through its interaction with the GABA-A receptor, the major inhibitory neurotransmitter receptor in the central nervous system. This interaction increases the receptor's affinity for its endogenous ligand, gamma-aminobutyric acid (GABA), leading to an increased influx of chloride ions into neurons, causing hyperpolarisation and a subsequent reduction in neuronal excitability. This results in soporific effect - sedation and anaesthesia.

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of Cl-.

Metabolic pathway

Chloralose is effectively a chloral generator which, in turn, affords trichloroethanol by metabolism. This is the narcotic agent. Sleep is induced in mice before death and therefore the compound is regarded as a humane mouse killer. It is particularly effective when a quick clearout is required but there is evidence that mice can become tolerant.

Degradation

Chloralose is hydrolysed by acid and base to glucose and chloral (2, trichloroacetaldehyde).

Pesticide Type

Rodenticide; Avicide; Repellent

50-99-7
104-15-4
75-87-6
15879-93-3
Synthesis of α-Chloralose from D(+)-Glucose and p-Toluenesulfonic acid and Chloral

α-Chloralose Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 216)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 18080918076 800078821@qq.com China 9706 55

View Latest Price from α-Chloralose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
alpha-Chloralose USP/EP/BP pictures 2026-08-20 alpha-Chloralose USP/EP/BP
15879-93-3
$1.10 1g 99.9% 100 Tons Min Dideu Industries Group Limited
alpha-Chloralose pictures 2026-05-28 alpha-Chloralose
15879-93-3
$100.00-280.00 10kg 99.9% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Alpha-Chloralose pictures 2025-06-20 Alpha-Chloralose
15879-93-3
$100.00 1KG 98% 1000tons/month Hebei Yanxi Chemical Co., Ltd.
  • alpha-Chloralose pictures
  • alpha-Chloralose
    15879-93-3
  • $100.00-280.00
  • 99.9%
  • Hebei Chuanghai Biotechnology Co,.LTD
(r)-1,2-o-(2,2,2-trichloroethylidene)-alpha-d-glucofuranose 2-o-(2,2,2-trichloroethylidene)-(r)-alpha-d-glucofuranos 2-o-(2,2,2-trichloroethylidene)-(theta)-alpha-d-glucofuranos alfamat alpha-chloralos alphakil aphosal chloralosane chloroalosane D-Glucofuranose,1,2-O-(2,2,2-trichloroethylidene)-,(R)-.alpha. dulcidor kalmettumsomniferum krakalos monotrichlor-aethyliden-alpha-glucose murex perglucorat S-17086 somio alpha-Chloralose, 98+%, beta anomer ca 15% (R)-1,2-O-(2,2,2-Trichloroethylidene)-alpha-glucofuranose A-CHLORALOSE, SIGMAULTRA A-CHLORALOSE B-ANOMER <5% .alpha.-D-Glucofuranose, 1,2-O-(1R)-2,2,2-trichloroethylidene- à-chloralose chloralose (bsi,iso) ALPHA-CHLORALOSE,PURIFIED ALPHA-CHLORALOSE , SS ANOMER CA 15% alpha-Chloralose, 98+%, ~ anomer ca 15% alpha-Chloralose, tech. 85% Anhydro-D-glucochloral, Chloralose, 1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose α-Chloralose, Anhydro-D-glucochloral, Chloralose, 1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose 2-Chloralose a-D-Glucofuranose, 1,2-O-[(1R)-2,2,2-trichloroethylidene]- alpha-D-Glucofuranose ^a-Chloralose, 98+%, ^b anomer ca 15% ɑ-Chloralose, 98+%, β anomer ca 15% alpha-Chloralose (contains beta-isomer) chloralose (INN) (R)-1,2-O-(2,2,2-trichloroethylidene)-α-D-glucofuranose glucochloralose anhydroglucochloral alpha-Chloralose,97% Alfa-4(TM) α-Chloralose, 98%,anomer ca 15% ANHYDRO-D-GLUCOCHLORAL ANHYDROGLUCOCHLORAL CHLORALOSE CHLORALOSE, A- GLUCOCHLORAL GLUCOCHLORALOSE 1,2-O-[2,2,2-TRICHLOROETHYLIDENE]-ALPHA-D-GLUCOFURANOSE 1,2-O-(2,2,2-TRICHLOROETHYLIDENE)-D-GLUCOFURANOSE A-D-GLUCOCHLORALOSE A-D-GLUCOCHLOROLOSE A-CHLORALOSE ALPHA-D-CHLORALOSE ALPHA-D-(+)-GLUCOCHLORALOSE ALPHA-D-GLUCOCHLORALOSE ALFAMAT(R) ALFA-4(R) ALFA Z(R)