2,6-Dichloroquinoline
- CAS No.
- 1810-72-6
- Chemical Name:
- 2,6-Dichloroquinoline
- Synonyms
- 2,6-Dichloroquinoline;Quinoline, 2,6-dichloro-;2,6-Dichloroquinoline ,97%;2,6-
Dichloroquinoline;2,6-Dichloro-1-azanaphthalene;2,6-DICHLOROQUINOLINE ISO 9001：2015 REACH
- CBNumber:
- CB9712836
- Molecular Formula:
- C9H5Cl2N
- Molecular Weight:
- 198.05
- MDL Number:
- MFCD03427194
- MOL File:
- 1810-72-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 161-164 °C (lit.) |
|---|---|
| Boiling point | 172°C/13mmHg(lit.) |
| Density | 1.407±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | -0.48±0.43(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | 1S/C9H5Cl2N/c10-7-2-3-8-6(5-7)1-4-9(11)12-8/h1-5H |
| InChIKey | LPDFGLZUUCLXGM-UHFFFAOYSA-N |
| SMILES | Clc1ccc2nc(Cl)ccc2c1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2,6-Dichloroquinoline price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 557803 | 2,6-Dichloroquinoline 97% | 1810-72-6 | 1g | $77.4 | 2022-05-15 | Buy |
| Sigma-Aldrich | 557803 | 2,6-Dichloroquinoline 97% | 1810-72-6 | 5g | $200 | 2022-05-15 | Buy |
| TCI Chemical | D5429 | 2,6-Dichloroquinoline >98.0%(GC) | 1810-72-6 | 1g | $66 | 2026-04-30 | Buy |
| TCI Chemical | D5429 | 2,6-Dichloroquinoline >98.0%(GC) | 1810-72-6 | 5g | $260 | 2026-04-30 | Buy |
| Apolloscientific | OR307515 | 2,6-Dichloroquinoline 97% | 1810-72-6 | 1g | $21 | 2026-06-04 | Buy |
2,6-Dichloroquinoline Chemical Properties, Uses, Production
Chemical Properties
White to orange to tan crystal or powder
Uses
2,6-Dichloroquinoline may be used in the preparation of poly(quinoline-2,6-diyl), via electrochemical polymerization.
Synthesis Reference(s)
The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196i
General Description
2,6-Dichloroquinoline can be synthesized from 6-chloroquinoline. It can also be prepared from the corresponding 2-vinylaniline.
Synthesis
1810-67-9
1810-72-6
Synthesis of 2,6-dichloroquinoline: 180 mg of 6-chloroquinolin-2(1H)-one was dissolved in 3 mL of phosphorus oxychloride (POCl3) and the reaction mixture was heated to reflux for 3 h. The reaction was carried out on a rotary evaporator. Upon completion of the reaction, the excess POCl3 was removed by rotary evaporator.After the reaction mixture was cooled to room temperature, the residue was treated with ice water and the precipitated solid was collected by filtration and dried to give the product in the form of a green powder in 90% yield. The synthesis of the compound followed the general method described in claim 5. The theoretical mass-to-charge ratio (m/z) of the compound C9H5Cl2N was 198; the measured value was 198. LC-MS analysis showed that the m/z of the molecular ion peak [M+2]+ was 200.1. 1H NMR (400 MHz, DMSO-d6) δ ppm: 8.04 (1H, d, J = 7.8 Hz), 7.97 (1H, d, J = 8.8 Hz), 7.81 (1H, d, J = 1.9 Hz), 7.68 (1H, dd, J = 9.8 Hz, J = 2.9 Hz), 7.42 (1H, d, J = 8.8 Hz).
References
[1] Patent: US2011/190343, 2011, A1. Location in patent: Page/Page column 27
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 20, p. 7220 - 7231
[3] Journal of Medicinal Chemistry, 2002, vol. 45, # 14, p. 3130 - 3137
[4] Ann. Inst. Pasteur, 1930, vol. 44, p. 719,737
2,6-Dichloroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from 2,6-Dichloroquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 2,6-Dichloroquinoline
1810-72-6
|
$1.10-9.90 | 1KG | 99% min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-08-20 | 2,6-DICHLOROQUINOLINE
1810-72-6
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-07-06 | 2,6-DICHLOROQUINOLINE
1810-72-6
|
$3.00 | 1KG | 90%-99.9% | 1000kg | Career Henan Chemical Co |
-
- 2,6-Dichloroquinoline
1810-72-6
- $1.10-9.90
- 99% min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2,6-DICHLOROQUINOLINE
1810-72-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2,6-DICHLOROQUINOLINE
1810-72-6
- $3.00
- 90%-99.9%
- Career Henan Chemical Co
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