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8-Hydroxyguanosine

8-Hydroxyguanosine Structure
8-Hydroxyguanosine structure
CAS No.
3868-31-3
Chemical Name:
8-Hydroxyguanosine
Synonyms
8-OXO-G;8-OHG;8-OH-GUO;NSC 90393;RNA adduct;8-Hydroxy-Gr;8-OXOGUANOSINE;8-Oxo-D-guanosine;8-Hydroxyguanosine;7,8-dihydro-8-oxo-guanosin
CBNumber:
CB9734795
Molecular Formula:
C10H13N5O6
Molecular Weight:
299.24
MDL Number:
MFCD00216136
MOL File:
3868-31-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:56:34
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8-Hydroxyguanosine Properties

Melting point 232-235°C
Density 2.43±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) Water (Slightly, Heated,Sonicated)
form White to off-white powder.
pka 7.75±0.20(Predicted)
color White to Off-White
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P301+P310
Toxicity sce-hmn-lym 100 nmol/L MUREAV 403,223,1998

8-Hydroxyguanosine price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical O0661 8-Hydroxyguanosine 3868-31-3 50MG $321 2026-04-30 Buy
Cayman Chemical 89300 8-Hydroxyguanosine ≥98% 3868-31-3 1mg $40 2026-04-30 Buy
Cayman Chemical 89300 8-Hydroxyguanosine ≥98% 3868-31-3 5mg $132 2026-04-30 Buy
Cayman Chemical 89300 8-Hydroxyguanosine ≥98% 3868-31-3 10mg $246 2026-04-30 Buy
Cayman Chemical 89300 8-Hydroxyguanosine ≥98% 3868-31-3 25mg $561 2026-04-30 Buy
Product number Packaging Price Buy
O0661 50MG $321 Buy
89300 1mg $40 Buy
89300 5mg $132 Buy
89300 10mg $246 Buy
89300 25mg $561 Buy

8-Hydroxyguanosine Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro

Uses

It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells.

Definition

ChEBI: 8-Hydroxyguanosine is a purine nucleoside.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

in vivo

8-Hydroxyguanosine (60 mg/kg, i.p., 4 h before LPS (1 mg/kg) injected) attenuates the LPS-induced increase in serum levels of TNF-α and IL-18 in LPS-treated mice[4].

Animal Model:LPS-treated mice[4]
Dosage:60 mg/kg
Administration:i.p., 4 h before LPS (1 mg/kg) injected
Result:Attenuated the LPS-induced increase in serum levels of TNF-α and IL-18, but was not significant for IL-6 and IL-12p70 in mice.

IC 50

Human Endogenous Metabolite

8-Hydroxyguanosine Preparation Products And Raw materials

Raw materials

6H-Purin-6-one, 2,7-diamino-1,7-dihydro- 8-Aminoguanosine Guanosine

Preparation Products

8-Hydroxyguanosine Suppliers

Global( 102)Suppliers
Supplier Tel Email Country ProdList Advantage
Fuyang Ziyi Biological Pharmaceutical Co., Ltd. 19308655899; 19308655899 2677609105@qq.com China 500 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Hongene Biotech Corporation 021-64757213 info@hongene.com China 672 61
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd. 0371-85513397 info@granlen.com China 497 55
TianJin Alta Scientific Co., Ltd. 022-65378550-8551 contact@altascientific.com China 2772 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
Fuyang Ziyi Biological Pharmaceutical Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Hongene Biotech Corporation 61
Nanjing Chemlin Chemical Co., Ltd 64
Chemsky（shanghai）International Co.,Ltd. 50
T&W GROUP 58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd. 55
TianJin Alta Scientific Co., Ltd. 58
Bide Pharmatech Ltd. 60

View Lastest Price from 8-Hydroxyguanosine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-Hydroxyguanosine pictures 2026-07-27 8-Hydroxyguanosine
3868-31-3
 $73.00-228.00 99.89% 10g TargetMol Chemicals Inc.
8-HYDROXYGUANOSINE pictures 2024-08-14 8-HYDROXYGUANOSINE
3868-31-3
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

8-Hydroxyguanosine Spectrum

8-HYDROXYGUANOSINE(3868-31-3)1HNMR

3868-31-3(8-Hydroxyguanosine)Related Search:

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8-Oxo-D-guanosine 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione 2-amino-9-beta-d-ribofuranosylpurine-6,8(1h,9h)-dione 7,8-dihydro-8-oxo-guanosin 9h)-dione,2-amino-9-beta-d-ribofuranosyl-purine-8(1h 8-OHG 8-OH-GUO 8-OXOGUANOSINE 7,8-DIHYDRO-8-OXO-GUANOSINE 2-AMino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione NSC 90393 8-Hydroxy-Gr Guanosine, 7,8-dihydro-8-oxo- 8-HYDROXYGUANOSINE USP/EP/BP 8-Hydroxyguanosine, marker of oxidative stress,RNA adduct 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-hydroxy-1H-purin-6(9H)-one Endogenous Metabolite,8 Hydroxyguanosine,Inhibitor,8Hydroxyguanosine,8-Hydroxyguanosine,inhibit marker of oxidative stress RNA adduct 8-Hydroxyguanosine, biomarker for oxidative damage 8-Hydroxyguanosine, 10 mM in DMSO 8-OXO-G 8-Hydroxyguanosine 3868-31-3 C10H13N5O6 Carbohydrates & Derivatives Metabolites & Impurities Nucleotides and Nucleosides Bases & Related Reagents Labeling and Diagnostics Reagents Nucleotides