3-CHLOROBENZHYDROL
- CAS No.
- 63012-03-3
- Chemical Name:
- 3-CHLOROBENZHYDROL
- Synonyms
- AURORA KA-7060;3-CHLOROBENZHYDROL;3-CHLORODIPHENYLMETHANOL;(3-CHLORO-PHENYL)-PHENYL-METHANOL;Benzenemethanol, 3-chloro-α-phenyl-;Benzenemethanol, 3-chloro-a-phenyl-
- CBNumber:
- CB9744152
- Molecular Formula:
- C13H11ClO
- Molecular Weight:
- 218.68
- MDL Number:
- MFCD06201252
- MOL File:
- 63012-03-3.mol
| Melting point | 40 °C |
|---|---|
| Boiling point | 169°C/0.1mm |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 13.28±0.20(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 63012-03-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H303-H335 |
| Precautionary statements | P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HazardClass | IRRITANT |
3-CHLOROBENZHYDROL price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B405168 | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 1g | $310 | 2021-12-16 | Buy |
| AK Scientific | 9560AB | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 5g | $429 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0021690 | 3-CHLOROBENZHYDROL 95.00% | 63012-03-3 | 1G | $757.97 | 2021-12-16 | Buy |
| AK Scientific | 9560AB | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 10g | $805 | 2021-12-16 | Buy |
| Rieke Metals | NV00648 | 3-CHLOROBENZHYDROL | 63012-03-3 | 1g | $809 | 2021-12-16 | Buy |
3-CHLOROBENZHYDROL Chemical Properties,Uses,Production
Uses
(3-Chlorophenyl)(phenyl)methanol is useful as T cell activators to treat viral infections and proliferative disorders, such as cancer.
Synthesis
1016-78-0
63012-03-3
General procedure for the synthesis of 3-chlorodiphenylmethanol from 3-chlorobenzophenone: (1) To a mixed solution of ethanol (100 mL) and tetrahydrofuran (THF, 100 mL) of 3-chlorobenzophenone (10.0 g, 46.2 mmol), sodium borohydride (876 mg, 23.1 mmol) was slowly added at room temperature. The reaction mixture was stirred at room temperature for 3 h. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was poured into water and extracted with ethyl acetate. The organic phases were combined, washed with water and then dried over anhydrous magnesium sulfate. After filtration, the solvent was removed by distillation under reduced pressure to give 3-chlorodiphenylmethanol as a colorless oil in a yield of 9.53 g (94.4% yield). 1H-NMR (CDCl3) δ: 2.55 (1H, d, J = 3.6 Hz), 5.80 (1H, d, J = 3.6 Hz), 7.25 to 7.40 (9H, m).
References
[1] Organic Letters, 2000, vol. 2, # 5, p. 659 - 661
[2] Patent: EP1437344, 2004, A1. Location in patent: Page 48
[3] Recueil des Travaux Chimiques des Pays-Bas, 1912, vol. 31, p. 311
[4] Recueil des Travaux Chimiques des Pays-Bas, 1915, vol. 34, p. 162
[5] Recueil des Travaux Chimiques des Pays-Bas, 1919, vol. 38, p. 121
3-CHLOROBENZHYDROL Preparation Products And Raw materials
Raw materials
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Preparation Products
3-CHLOROBENZHYDROL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Changzhou uniringchem Co., Ltd. | +undefined13585446801 | sales@uniringchem.com | China | 69 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11598 | 64 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
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