3-Chlorobenzhydrol
- CAS No.
- 63012-03-3
- Chemical Name:
- 3-Chlorobenzhydrol
- Synonyms
- AURORA KA-7060;3-Chlorobenzhydrol;3-CHLORODIPHENYLMETHANOL;(3-CHLORO-PHENYL)-PHENYL-METHANOL;Benzenemethanol, 3-chloro-α-phenyl-;Benzenemethanol, 3-chloro-a-phenyl-
- CBNumber:
- CB9744152
- Molecular Formula:
- C13H11ClO
- Molecular Weight:
- 218.68
- MDL Number:
- MFCD06201252
- MOL File:
- 63012-03-3.mol
- MSDS File:
- SDS
| Melting point | 40 °C |
|---|---|
| Boiling point | 169°C/0.1mm |
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 13.28±0.20(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 63012-03-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H303-H335 |
| Precautionary statements | P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HazardClass | IRRITANT |
3-Chlorobenzhydrol price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-B405168-500MG | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 500mg | $275 | 2026-06-03 | Buy |
| TRC | TRC-B405168-1G | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 1g | $421 | 2026-06-03 | Buy |
| TRC | TRC-B405168-100MG | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 100mg | $65 | 2026-06-03 | Buy |
| Biosynth | NCA01203 | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 0.25g | $250 | 2026-06-04 | Buy |
| Biosynth | NCA01203 | (3-Chlorophenyl)(phenyl)methanol | 63012-03-3 | 2.5g | $855.5 | 2026-06-04 | Buy |
3-Chlorobenzhydrol Chemical Properties,Uses,Production
Uses
(3-Chlorophenyl)(phenyl)methanol is useful as T cell activators to treat viral infections and proliferative disorders, such as cancer.
Synthesis
1016-78-0
63012-03-3
General procedure for the synthesis of 3-chlorodiphenylmethanol from 3-chlorobenzophenone: (1) To a mixed solution of ethanol (100 mL) and tetrahydrofuran (THF, 100 mL) of 3-chlorobenzophenone (10.0 g, 46.2 mmol), sodium borohydride (876 mg, 23.1 mmol) was slowly added at room temperature. The reaction mixture was stirred at room temperature for 3 h. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was poured into water and extracted with ethyl acetate. The organic phases were combined, washed with water and then dried over anhydrous magnesium sulfate. After filtration, the solvent was removed by distillation under reduced pressure to give 3-chlorodiphenylmethanol as a colorless oil in a yield of 9.53 g (94.4% yield). 1H-NMR (CDCl3) δ: 2.55 (1H, d, J = 3.6 Hz), 5.80 (1H, d, J = 3.6 Hz), 7.25 to 7.40 (9H, m).
References
[1] Organic Letters, 2000, vol. 2, # 5, p. 659 - 661
[2] Patent: EP1437344, 2004, A1. Location in patent: Page 48
[3] Recueil des Travaux Chimiques des Pays-Bas, 1912, vol. 31, p. 311
[4] Recueil des Travaux Chimiques des Pays-Bas, 1915, vol. 34, p. 162
[5] Recueil des Travaux Chimiques des Pays-Bas, 1919, vol. 38, p. 121
3-Chlorobenzhydrol Preparation Products And Raw materials
Raw materials
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Preparation Products
3-Chlorobenzhydrol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Hebei Summedchem Co.,Ltd | 0319-5801333-8008 15630992918 | sales@summedchem.com | China | 1000 | 58 |
| Shanghai QianYan Bio-technology Co., Ltd | 02781293128 | orders@biochemsafebuy.com | China | 9904 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Dalian lichuang Chemical Co., Ltd | 0411-0411-00000000 13644282108 | 3500508746@qq.com | China | 2942 | 55 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
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