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5-ETHYL-2-THIOURACIL

CAS No.
34171-37-4
Chemical Name:
5-ETHYL-2-THIOURACIL
Synonyms
5-ETHYL-2-THIOURACIL;5-Ethyl-2-thiouracil ,98%;5-ETHYL-2-THIOURACIL USP/EP/BP;5-Ethyl-2-thioxo-2,3-dihydropyriMidin-4(1H)-one;4(1H)-Pyrimidinone, 5-ethyl-2,3-dihydro-2-thioxo-;5-ethyl-2-sulfanylidene-1,2,3,4-tetrahydropyriMidin-4-one
CBNumber:
CB9761278
Molecular Formula:
C6H8N2OS
Molecular Weight:
156.21
MDL Number:
MFCD00079592
MOL File:
34171-37-4.mol
MSDS File:
SDS
Last updated:2026-05-28 06:06:36
Product description Number Pack Size Price
5-Ethyl-2-thiouracil >95%(HPLC) TRC-E926855-50MG 50mg $89
5-Ethyl-2-thiouracil >95%(HPLC) TRC-E926855-250MG 250mg $184
5-Ethyl-2-thiouracil 98% OR926014 250mg $21
5-Ethyl-2-thiouracil 98% AS35790 1g $124
5-Ethyl-2-thiouracil 98% AS35790 5g $366
More product size

5-ETHYL-2-THIOURACIL Properties

Melting point 191-193℃
Density 1.29±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka 7.69±0.25(Predicted)
color Pale Yellow to Pale Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
WGK Germany  3
HS Code  29335990

5-ETHYL-2-THIOURACIL price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-E926855-50MG 5-Ethyl-2-thiouracil >95%(HPLC) 34171-37-4 50mg $89 2026-06-03 Buy
TRC TRC-E926855-250MG 5-Ethyl-2-thiouracil >95%(HPLC) 34171-37-4 250mg $184 2026-06-03 Buy
Apolloscientific OR926014 5-Ethyl-2-thiouracil 98% 34171-37-4 250mg $21 2026-06-04 Buy
Activate Scientific AS35790 5-Ethyl-2-thiouracil 98% 34171-37-4 1g $124 2026-06-04 Buy
Activate Scientific AS35790 5-Ethyl-2-thiouracil 98% 34171-37-4 5g $366 2026-06-04 Buy
Product number Packaging Price Buy
TRC-E926855-50MG 50mg $89 Buy
TRC-E926855-250MG 250mg $184 Buy
OR926014 250mg $21 Buy
AS35790 1g $124 Buy
AS35790 5g $366 Buy

5-ETHYL-2-THIOURACIL Chemical Properties,Uses,Production

Chemical Properties

Off-white solid

Uses

5-Ethyl-2-thiouracil is a modified nucleobase and a versatile reactant used in the synthesis. It was used as a reactant in the inhibition of Hepatitis B virus (HBV) replication.

Synthesis

Ethyl butyrate

105-54-4

Carbamimidothioic acid

17356-08-0

Ethyl formate

109-94-4

5-ETHYL-2-THIOURACIL

34171-37-4

Step D75: Synthesis of 5-ethyl-2-thio-2,3-dihydro-4(1H)-pyrimidinone 1. To a suspension of potassium tert-butanolate (12.08 g, 108 mmol) in THF (40 mL) under nitrogen protection was slowly added dropwise a mixed solution of ethyl butyrate (5.69 mL, 43.0 mmol) and ethyl formate (6.93 mL, 86 mmol) in ether (40.0 mL). 2. The reaction mixture was stirred at room temperature for 3 hours. 3. Upon completion of the reaction, the solvent was removed under reduced pressure to give an oily residue. 4. The residue was dissolved in isopropanol (350 mL) and thiourea (6.55 g, 86 mmol) was added. 5. The mixture was heated to reflux and stirred overnight. 6. At the end of the reaction, the reaction solution was concentrated under vacuum to give a solid product. 7. The solid product was dissolved in water and the pH was adjusted to 4 with acetic acid (AcOH). 8. 8. The aqueous phase was extracted with dichloromethane (DCM) and the organic layers were combined. 9. The organic layer was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give 5-ethyl-2-thiouracil (5.5 g, 82% yield) as a pink solid.

References

[1] Patent: WO2012/76435, 2012, A1. Location in patent: Page/Page column 49

Global( 52)Suppliers
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Shaanxi Dideu Medichem Co. Ltd
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career henan chemical co
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Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Nanjing Huang Tai Pharmaceutical Technology Co. Ltd. 025-58803135 18551845925 3569572487@qq.com China 391 58

View Lastest Price from 5-ETHYL-2-THIOURACIL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Ethyl-2-thiouracil pictures 2024-08-11 5-Ethyl-2-thiouracil
34171-37-4
$1.00 1Kg 98% 20T Shaanxi Dideu Medichem Co. Ltd
5-ETHYL-2-THIOURACIL pictures 2021-07-13 5-ETHYL-2-THIOURACIL
34171-37-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-ETHYL-2-THIOURACIL pictures 2021-07-10 5-ETHYL-2-THIOURACIL
34171-37-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-ETHYL-2-THIOURACIL 5-Ethyl-2-thiouracil ,98% 5-ethyl-2-sulfanylidene-1,2,3,4-tetrahydropyriMidin-4-one 5-Ethyl-2-thioxo-2,3-dihydropyriMidin-4(1H)-one 4(1H)-Pyrimidinone, 5-ethyl-2,3-dihydro-2-thioxo- 5-ETHYL-2-THIOURACIL USP/EP/BP 34171-37-4 Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides BioChemical Biochemicals and Reagents