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2-Thiouracil

2-Thiouracil Structure
2-Thiouracil structure
CAS No.
141-90-2
Chemical Name:
2-Thiouracil
Synonyms
TU;Thiouracil;2-thioxo-2,3-dihydropyriMidin-4(1H)-one;DERACIL;Antagothyroid;2-Mercapto-4-pyrimidinol;2-Mercapto-4-pyriMidinone;4-Hydroxy-2-pyrimidinethiol;2-Sulfanylidene-1H-pyrimidin-4-one;2-TU
CBNumber:
CB5769908
Molecular Formula:
C4H4N2OS
Molecular Weight:
128.15
MDL Number:
MFCD00006039
MOL File:
141-90-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-15 20:54:36
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2-Thiouracil Properties

Melting point >300 °C (lit.)
Density 1.368 (estimate)
bulk density 600kg/m3
refractive index 1.7000 (estimate)
storage temp. Store below +30°C.
solubility 7.9g/l
form Fine Crystalline Powder
pka pKa 7.46 (Uncertain)
color White to cream
biological source synthetic
Water Solubility 0.5 g/L
λmax 271nm(H2O)(lit.)
Merck 14,9366
BRN 112227
InChI 1S/C4H4N2OS/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
InChIKey ZEMGGZBWXRYJHK-UHFFFAOYSA-N
SMILES O=C1NC(=S)NC=C1
CAS DataBase Reference 141-90-2(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII 59X161SCYL
Proposition 65 List Thiouracil
IARC 2B (Vol. Sup 7, 79) 2001
NIST Chemistry Reference 2-Thiouracil(141-90-2)
EPA Substance Registry System Thiouracil (141-90-2)
UNSPSC Code 41106305
NACRES NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P281
PPE Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  Xn,T
Risk Statements  40-45-20/21/22
Safety Statements  36/37-53-45
WGK Germany  3
RTECS  YR1575000
Autoignition Temperature 570°C
TSCA  TSCA listed
HS Code  29335995
Storage Class 11 - Combustible Solids
Hazard Classifications Carc. 2
Hazardous Substances Data 141-90-2(Hazardous Substances Data)
NFPA 704
0
1 0

2-Thiouracil price More Price(84)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T7750 2-Thiouracil ≥99% 141-90-2 25g $67.6 2026-04-30 Buy
Sigma-Aldrich T7750 2-Thiouracil ≥99% 141-90-2 1kg $887 2026-04-30 Buy
Sigma-Aldrich 8.21120 2-Thiouracil for synthesis 141-90-2 100G $73.7 2026-04-30 Buy
Sigma-Aldrich 8.21120 2-Thiouracil for synthesis 141-90-2 500G $328 2026-04-30 Buy
Sigma-Aldrich 8.21120 2-Thiouracil for synthesis 141-90-2 1KG $579 2026-04-30 Buy
Product number Packaging Price Buy
T7750 25g $67.6 Buy
T7750 1kg $887 Buy
8.21120 100G $73.7 Buy
8.21120 500G $328 Buy
8.21120 1KG $579 Buy

2-Thiouracil Chemical Properties,Uses,Production

Chemical Properties

white to cream fine crystalline powder

Uses

Reagent used in the preparation of Antithyroid agents.

Uses

antiviral, thyroid depressant

Uses

2-Thiouracil has been used in the synthesis and characterization of silver colloid and film substrates and their applications in surface-enhanced Raman scattering (SERS)

Definition

ChEBI: A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.

Biochem/physiol Actions

2-Thiouracil is a thio-derivative of uracil, a pyrimidine nucleobase. It acts as an anticancer, antithyroid, and antiviral agent. 2-Thiouracil is a selective melanoma-seeker and competitive inhibitor of neuronal nitric oxide synthase. It also forms complexes with transition metals such as gold (Au), Chromium (Cr), Zinc (Zn), and Silver (Ag).

Safety Profile

Moderately toxic by ingestion. Human teratogenic effects by unspecified routes: developmental abnormalities of the central nervous system, craniofacial area, and endocrine system. Human reproductive effects by unspecified route: effects on newborn, including viabllity index changes. Experimental teratogenic effects. Other experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. Used in the treatment of hyperthyroidism, angina pectoris, and congestive heart failure. See also MERCAPTANS and KETONES.

Purification Methods

Crystallise 2-thiouracil from water or EtOH. [Beilstein 24 H 323, 24 I 315, 24 II 171, 24 III/IV 1237.]

2-Thiouracil Preparation Products And Raw materials

Raw materials

Sodium Methoxide Thiourea 4-Amino-2-mercaptopyrimidine 2-Thiouridine

Preparation Products

Pyrimidin-4-ol 4-Chloro-N-methylpyrimidin-2-amine N-(4-Aminopyrimidin-2-yl)-N-methylamine 5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine 4-Bromopyrimidine
4-Thiouracil 4-Hydroxypyrimidine 4-Pyrimidinol Benzyl-(2-methylsulfanyl-pyrimidin-4-yl)-amine 4-Chloro-2-(methylsulfonyl)pyrimidine
5-Bromo-4-chloro-2-methanesulfonyl-pyrimidine 2-Methylthio-4-pyrimidinol 4-Chloro-2-methylthiopyrimidine Dithiouracil 5-(morpholinomethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
4-Hydroxy-2-phenylpyrimidine

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2-Thiouracil Suppliers

Global( 582)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Habo Medical Technology Co., Ltd. 13376080562 13376090521 sales@habotech.com China 726 60
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 13396369453 18678026865 sdfantai@163.com China 904 58
Huangshi Jingsheng Biotechnology Co., Ltd. 17771199833; 17771199833 351013952@qq.com China 3813 58
Suzhou Tianhong Medicine Chemical Technology Co.,Ltd. 18949937116 dongye.huaxue@126.com China 143 58
Wuhan pushida biotechnology co., Ltd 18163336578 2139086656@qq.com China 2240 58
Lianyungang Langrun Chemical Technology Co., Ltd. 17705136709 343200474@qq.com China 15 58
Nanjing Optimal New Materials Technology Co., Ltd. 173-40521416 17340521416 1757224788@qq.com China 2000 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Supplier Advantage
Nanjing Habo Medical Technology Co., Ltd. 60
Weifang Siyuan Chemical Co., Ltd. 58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 58
Huangshi Jingsheng Biotechnology Co., Ltd. 58
Suzhou Tianhong Medicine Chemical Technology Co.,Ltd. 58
Wuhan pushida biotechnology co., Ltd 58
Lianyungang Langrun Chemical Technology Co., Ltd. 58
Nanjing Optimal New Materials Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62

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View Lastest Price from 2-Thiouracil manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Thiouracil pictures 2026-09-11 2-Thiouracil
141-90-2
 $66.00-99.00 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2-Thiouracil pictures 2026-09-04 2-Thiouracil
141-90-2
 1Kg 98% 20Ton Xinxiang Aurora Biotechnology Co.,Ltd.
2-Thiouracil pictures 2026-08-21 2-Thiouracil
141-90-2
 $250.00-268.00 1kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
  • 2-Thiouracil pictures
  • 2-Thiouracil
    141-90-2
  • $66.00-99.00
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • 2-Thiouracil pictures
  • 2-Thiouracil
    141-90-2
  • 98%
  • Xinxiang Aurora Biotechnology Co.,Ltd.
  • 2-Thiouracil pictures
  • 2-Thiouracil
    141-90-2
  • $250.00-268.00
  • 99%
  • Hebei Dangtong Import and export Co LTD

2-Thiouracil Spectrum

2-Thiouracil(141-90-2)MS2-Thiouracil(141-90-2)1HNMR2-Thiouracil(141-90-2)13CNMR2-Thiouracil(141-90-2)IR12-Thiouracil(141-90-2)IR22-Thiouracil(141-90-2)Raman

141-90-2(2-Thiouracil)Related Search:

Pyrimidine 2-(2-Aminoethyl)isothiourea dihydrobromide 1-PHENYL-2-THIOUREA Tizoxanide-d4 Tiotropium D3 iodide
Thiosemicarbazide Chlorophosphonazo III 5-PROPYL-2-THIOURACIL 5-METHYL-2-THIOURACIL 6-AMINO-2-THIOURACIL MONOHYDRATE,6-AMINO-2-THIOURACIL HYDRATE
5,6-DIAMINO-2-THIOURACIL,4,5-DIAMINO-2-THIOURACIL Malathion 5,6-DIMETHYL-2-THIOURACIL 5-ETHYL-2-THIOURACIL 6-AMINO-2-THIOURACIL,4-Amino-2-thiouracil
6-Formyl-2-thiouracil 6-BENZYL-2-THIOURACIL 5-METHYL-2-THIOURIDINE

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2-Thiouracil Vetec(TM) reagent grade, 99% 2-ThiouraCll 4-HYDROXY-2-MERCAPTOPYRIMIDINE 4-HYDROXY-2-THIOPYRIMIDINE 2-MERCAPTO-4-PYRIMIDONE 2-MERCAPTO-4-HYDROXYPYRIMIDINE 2-thio-uraci 2-TU 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo- 4(1H)-Pyrimidinone,2,3-dihydro-2-thioxo- 4-hydroxy-2(1h)-pyrimidinethione 4-Pyrimidinol, 2-mercapto- 6-Hydroxy-2-mercaptopyrimidine 6-Thiouracil Antagothyroil nci-c01490 Nobilen Thiouraci tiouracyl NSC 290412 NSC 290413 NSC 290414 2-Mercapto-4-hydroxypyrimidine 2-Mercapto-4-pyrimidone 2-THIOURACIL 2,3-dihydro-2-thioxo-4(1h)-pyrimidinone 2,3-dihydro-2-thioxo-4(1h)-pyrimidinon Thiourea pyriMidine 2-Thiouracil, TU 2-mercapto-4(1h)-pyrimidinone 2-mercapto-4-pyrimidino 2-Mercaptopyrimid-4-one 2-Sulfanyl-4-pyrimidinol 2-Thio-1,3-pyrimidin-4-one 2-thio-2,4-(1h,3h)-pyrimidinedione 2-thio-4-oxo-1,3-pyrimidine 2-thio-4-oxypyrimidine 2-thio-6-oxypyrimidine Uracil, 2-thio- 4-HYDROXY-2-MERCAPTOPYRIMIDINE / 2-THIOURACIL 2-THIO-URACYLE THIURACIL 2-THIOURACIL VETRANAL, 250 MG 2-ThiouracilForSynthesis 2-Thiouracil, 98+% 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo- (9CI) 2-HYDROXY-2-MERCAPTOPYRIMIDINE 2-THIOURACIL extrapure 2-Thiouracil ,99% 2-Thioxo-2,3-dihydro-1H-pyrimidin-4-one 2-sulfanylidene-1,2,3,4-tetrahydropyriMidin-4-one NSC 19473 2-THIOURACIL, [4-HYDROXY-2-MERCAPTOPYRIMIDINE] Thiouracil Thiouracil 2-Thiouracil > 2-THIOURACIL FOR SYNTHESIS 500 G 2-THIOURACIL FOR SYNTHESIS 1 KG hiouracil TIANFU CHEM--2-Thiouracil