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2-Bromoquinoline-4-carboxylic acid

CAS No.
15733-87-6
Chemical Name:
2-Bromoquinoline-4-carboxylic acid
Synonyms
2-Bromoquinoline-4-carboxylic acid;4-Quinolinecarboxylic acid, 2-bromo-
CBNumber:
CB9845491
Molecular Formula:
C10H6BrNO2
Molecular Weight:
252.06
MDL Number:
MFCD08705669
MOL File:
15733-87-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:56:37

2-Bromoquinoline-4-carboxylic acid Properties

Melting point 175-176 °C(Solv: ethanol (64-17-5))
Boiling point 394.7±27.0 °C(Predicted)
Density 1.732±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 2.17±0.10(Predicted)
Appearance Off-white to gray Solid
InChI InChI=1S/C10H6BrNO2/c11-9-5-7(10(13)14)6-3-1-2-4-8(6)12-9/h1-5H,(H,13,14)
InChIKey LUHABDKNXNXNTO-UHFFFAOYSA-N
SMILES N1C2C(=CC=CC=2)C(C(O)=O)=CC=1Br

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933499090

2-Bromoquinoline-4-carboxylic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR906018 2-Bromoquinoline-4-carboxylic acid 97% 15733-87-6 250mg $63 2026-06-04 Buy
Apolloscientific OR906018 2-Bromoquinoline-4-carboxylic acid 97% 15733-87-6 1g $190 2026-06-04 Buy
Matrix Scientific 073878 2-Bromoquinoline-4-carboxylic acid 15733-87-6 250.00mg $38 2026-05-18 Buy
Matrix Scientific 073878 2-Bromoquinoline-4-carboxylic acid 15733-87-6 1.00g $133 2026-05-18 Buy
Matrix Scientific 073878 2-Bromoquinoline-4-carboxylic acid 15733-87-6 5.00g $535 2026-05-18 Buy
Product number Packaging Price Buy
OR906018 250mg $63 Buy
OR906018 1g $190 Buy
073878 250.00mg $38 Buy
073878 1.00g $133 Buy
073878 5.00g $535 Buy

2-Bromoquinoline-4-carboxylic acid Chemical Properties, Uses, Production

Synthesis

2-Hydroxy-4-quinolincarboxylic acid

15733-89-8

2-BROMOQUINOLINE-4-CARBOXYLIC ACID

15733-87-6

General procedure for the synthesis of 2-bromoquinoline-4-carboxylic acid from 2-quinolone-4-carboxylic acid: a mixture of 2-hydroxyquinoline-4-carboxylic acid (4.0 g, 21.2 mmol) and phosphorus tribromide (25.0 g, 87.2 mmol) in toluene (40 mL) was heated and refluxed for 3 hours at 100°C. Upon completion of the reaction, the mixture was cooled to room temperature and carefully poured into crushed ice. The mixture was extracted with ethyl acetate (2 x 250 mL), the organic phases were combined, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was dissolved in 1N sodium hydroxide solution (150 mL) and extracted with ethyl acetate (2 x 100 mL). The aqueous phase was adjusted to pH 3 with 1N hydrochloric acid and a white solid was precipitated. The solid was collected by filtration, washed with water and dried to give 2-bromoquinoline-4-carboxylic acid (3.0 g, 56% yield) as a white solid.

References

[1] Patent: WO2006/69063, 2006, A1. Location in patent: Page/Page column 98
[2] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 589
[3] Patent: EP2325181, 2011, A1. Location in patent: Page/Page column 61

2-Bromoquinoline-4-carboxylic acid Preparation Products And Raw materials

2-Bromoquinoline-4-carboxylic acid Suppliers

Global Suppliers ( 52)
Supplier Tel Email Country ProdList Advantage
SHENZHEN REISCH BIOTECH CO., LTD 0755-0755-28609002 15112530219 1179151648@qq.com China 236 58
Shanghai Synthfine Chemical Co.,Ltd 15921303235 sales@synthfine.com China 999 58
Nanjing ERan Biological Pharmaceutical Co., Ltd. 13770809694 googlexu_0114@sina.com China 992 58
NovoChemy Ltd. 86-(0)21-31261262 373522135 sales@novochemy.com China 6491 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
JinJin Le Chemical Co., Ltd 18001959627(微信同号) 18001959627 jjlchem2@163.com China 9890 58
Sichuan BoYou Biotechnology Co., Ltd. 028-65791793 18140026355 568470422@qq.com China 9961 58
Suzhou Nuoouman Biological Technology Co., Ltd. 15026866316 180642609@qq.com China 4966 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58

View Latest Price from 2-Bromoquinoline-4-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-BROMOQUINOLINE-4-CARBOXYLIC ACID pictures 2026-06-30 2-BROMOQUINOLINE-4-CARBOXYLIC ACID
15733-87-6
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd

2-Bromoquinoline-4-carboxylic acid Spectrum

4-Quinolinecarboxylic acid, 2-bromo- 2-Bromoquinoline-4-carboxylic acid 15733-87-6