1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)-
- CAS No.
- 869725-57-5
- Chemical Name:
- 1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)-
- Synonyms
- 5-(trifluoroMethyl)-2,3-dihydro-1H-inden-1-ol;2,3-Dihydro-5-(trifluoromethyl)-1H-inden-1-ol;1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)-
- CBNumber:
- CB9958353
- Molecular Formula:
- C10H9F3O
- Molecular Weight:
- 202.17
- MDL Number:
- MFCD09839598
- MOL File:
- 869725-57-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)- price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00GRH5 | 5-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-ol 95+% | 869725-57-5 | 100mg | $1275 | 2026-05-28 | Buy |
| ACHEMBLOCK | S88045 | 5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol 95% | 869725-57-5 | 100MG | $290 | 2026-05-27 | Buy |
| ACHEMBLOCK | S88045 | 5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol 95% | 869725-57-5 | 250MG | $460 | 2026-05-27 | Buy |
| ACHEMBLOCK | S88045 | 5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol 95% | 869725-57-5 | 1G | $1380 | 2026-05-27 | Buy |
| Crysdot | CD12021959 | 5-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-ol 95+% | 869725-57-5 | 1g | $688 | 2026-05-27 | Buy |
1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)- Chemical Properties, Uses, Production
Synthesis
150969-56-5
869725-57-5
Step F Synthesis of 5-(trifluoromethyl)indan-1-ol: To a solution of 5-(trifluoromethyl)indan-1-one (0.7 g, 3 mmol) in THF (5 mL) was slowly added sodium borohydride (0.1 g, 3 mmol), followed by the dropwise addition of MeOH (1 mL), under the cooling conditions in an ice bath. The reaction mixture was stirred at room temperature for 30 min before the reaction was quenched with saturated aqueous NaHCO3 solution. The reaction solution was extracted with EtOAc (2×) and the combined organic phases were washed with saturated brine, dried over anhydrous MgSO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with 20% EtOAc/hexane as eluent to afford the target compound 5-(trifluoromethyl)indan-1-ol (0.65 g, 92%) as a colorless oil.LC/MS analysis: calculated value of C10H9F3O (M+H)+ 203; measured value 185.1 (M+H-H2O)+.
References
[1] Patent: US2005/261310, 2005, A1. Location in patent: Page/Page column 25
[2] ACS Medicinal Chemistry Letters, 2010, vol. 1, # 9, p. 483 - 487
[3] Angewandte Chemie - International Edition, 2011, vol. 50, # 7, p. 1702 - 1706
1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)- Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Trylead Chemical Technology Co.,LTD | 0571-87086220 13516718938 | zyf@trylead-chem.com | China | 300 | 64 |
| LABTER PHARMATECH(BEIJING) CO.,LTD | 010-56330744 18310155299 | sales@labter.com.cn | China | 19999 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Anmike Chemical Co. Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 9988 | 55 |
| Bejing Famous Pharmaceutical Technology Co., Ltd. | 010-80339217; 13331045123 | 2559355526@qq.com | China | 14180 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Hebei Boxin Biotechnology Co. , Ltd. | 19131160546 | 2681315246@qq.com | China | 13193 | 58 |
