4-O-β-D-ガラクトピラノシル-α-D-グルコピラノース·水和物 化学特性,用途語,生産方法
外観
白色, 結晶性粉末〜粉末
溶解性
水に易溶 (20g/100ml 15℃), エタノール, エーテルに不溶。水に溶けやすく、エタノール,ジエチルエーテルおよびクロロホルムにほとんど溶けない。
用途
糖類研究用。医薬品原料。
用途
細菌培養基剤、医薬原料(賦形剤）。
化学的特性
White powder
使用
alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.
定義
A sugar that occurs in many
plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and
a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme
invertase. Since this mixture has a different
optical rotation (levorotatory) than the
original sucrose, the mixture is called invert sugar.
調製方法
A suspension of a-lactose monohydrate crystals in a lactose solution
is atomized and dried in a spray drier. Approximately 10–20%
of the total amount of lactose is in solution and the remaining
80–90% is present in the crystalline form. The spray-drying process
predominantly produces spherical particles. The compactibility of
the material and its flow characteristics are a function of the
primary particle size of the lactose monohydrate and the amount of
amorphous lactose.
応用例（製薬）
Spray-dried lactose is widely used as a binder, filler-binder, and flow
aid in direct compression tableting.
安全性
Lactose is widely used in pharmaceutical formulations as a diluent
in oral capsule and tablet formulations. It may also be used in
intravenous injections.
Adverse reactions to lactose are largely due to lactose intolerance,
which occurs in individuals with a deficiency of the enzyme
lactase.
貯蔵
Spray-dried lactose should be stored in a well-closed container in a
cool, dry place.
不和合性
Lactose is a reducing sugar. The amorphous lactose, which is the
most reactive form of lactose present in spray-dried lactose, will
interact more readily than conventional crystalline grades.
Typical reactions include the Maillard reaction with either
primary or secondary amines.
4-O-β-D-ガラクトピラノシル-α-D-グルコピラノース·水和物 上流と下流の製品情報
原材料
準備製品