6-メチルイソキノリン
6-メチルイソキノリン 物理性質
- 融点 :
- 85.5°C
- 沸点 :
- 246.29°C (estimate)
- 比重(密度) :
- 1.0584 (estimate)
- 屈折率 :
- 1.6103 (estimate)
- 酸解離定数(Pka):
- 5.85±0.10(Predicted)
- 外見 :
- solid
- 色:
- Beige
- InChI:
- InChI=1S/C10H9N/c1-8-2-3-10-7-11-5-4-9(10)6-8/h2-7H,1H3
- InChIKey:
- PPEJLOXOMBAXES-UHFFFAOYSA-N
- SMILES:
- C1C2=C(C=C(C)C=C2)C=CN=1
- CAS データベース:
- 42398-73-2(CAS DataBase Reference)
6-メチルイソキノリン 価格
もっと(11)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOOR8565 |
6-メチルイソキノリン
6-Methylisoquinoline |
42398-73-2 |
250mg |
￥9600 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOOR8565 |
6-メチルイソキノリン
6-Methylisoquinoline |
42398-73-2 |
1g |
￥26900 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS126280 |
6-メチルイソキノリン
6-Methylisoquinoline |
42398-73-2 |
1g |
￥29400 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBHC-6025 |
6-メチルイソキノリン
6-Methylisoquinoline |
42398-73-2 |
1g |
￥15000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS126280 |
6-メチルイソキノリン
6-Methylisoquinoline |
42398-73-2 |
5g |
￥99400 |
2024-03-01 |
購入 |
6-メチルイソキノリン 化学特性,用途語,生産方法
化学的特性
Light beige powder
使用
6-Methylisoquinoline (cas# 42398-73-2) is a useful reagent for the green preparation of polyfluoroarylated heterocyclic compounds.
製造方法
A benzene solution (50 ml, CAUTION) of equimolar amounts of p-tolualdehyde (8.4 g, 0.07 mol) and aminoacetaldehyde dimethyl acetal (7.35 g, 0.07 mol) is refluxed overnight into a Dean and Stark trap. The solution is evaporated in vacuo and then twice evaporated again with added benzene and the viscous oil dissolved in dry tetrahydrofuran. This solution is cooled to - 10 °C and 1 equivalent of ethyl chloroformate (7. 1 ml, 0.07 mol) is added with rapid stirring and the mixture stirred for a further 5 minutes. The cooling bath is removed and 1.2 equivalents of trimethyl phosphite ( 10.5 ml, 0.09 mol) is added with stirring. The solution is stirred at room temperature for 1 5 hours and then evaporated t o an oil. The oil is then re-evaporated twice with added toluene to remove traces of trimethyl phosphite. The oil is dissolved in dry dichloromethane, 6 equivalents of titanium(1v) chloride (50 ml, 0.45 mol) is added and the solution refluxed for 36 hours under a drying tube. The cooled solution is shaken with 1 equivalent of aqueous sodium hydroxide solution to neutrality, whereupon titanium(1v) oxide precipitates as a white solid. The filtered organic layer is extracted with 3 M hydrochloric acid, and the extract is washed with dichloromethane, basified strongly with aqueous alkali, and extracted with dichloromethane. This organic extract is dried over anhydrous sodium sulphate and evaporated to afford 6-methylisoquinoline (yield 7 1 %, m.p. 88 °C).
6-メチルイソキノリン 上流と下流の製品情報
原材料
準備製品
6-メチルイソキノリン 生産企業
Global( 96)Suppliers
42398-73-2(6-メチルイソキノリン)キーワード:
- 42398-73-2
- 6-Methylisoquinoline 98%
- 6-Methylisoquinoline
- Isoquinoline, 6-methyl-
- 6-Methylisoquinoline ,98%
- 6-Methylisoquinoline ISO 9001：2015 REACH
- 3,4,4-trimethylpentan-2-one
- 6-メチルイソキノリン