N-[(S)-(4-니트로페녹시)페녹시포스피닐]-L-알라닌1-메틸에틸에스테르
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N-[(S)-(4-니트로페녹시)페녹시포스피닐]-L-알라닌1-메틸에틸에스테르 속성
- 녹는점
- 62-66℃
- 끓는 점
- 514.3±60.0 °C(Predicted)
- 밀도
- 1.302
- 저장 조건
- 2-8°C
- 용해도
- 디클로로메탄, 에틸아세테이트, 메탄올에 용해됨
- 산도 계수 (pKa)
- -5.78±0.70(Predicted)
- 물리적 상태
- Solid
- 색상
- White to off-white
안전
N-[(S)-(4-니트로페녹시)페녹시포스피닐]-L-알라닌1-메틸에틸에스테르 C화학적 특성, 용도, 생산
용도
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.N-[(S)-(4-니트로페녹시)페녹시포스피닐]-L-알라닌1-메틸에틸에스테르 준비 용품 및 원자재
원자재
준비 용품
N-[(S)-(4-니트로페녹시)페녹시포스피닐]-L-알라닌1-메틸에틸에스테르 공급 업체
글로벌( 51)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21614 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29847 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 |
mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23541 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 |
sales@newcanbio.com | China | 9985 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 |
sales@tnjchem.com | China | 25356 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 |
sales@anikare.com | China | 9941 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 |
product@acmec-e.com | China | 33338 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40066 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 |
info@dycnchem.com | China | 53899 | 58 |
N-[(S)-(4-니트로페녹시)페녹시포스피닐]-L-알라닌1-메틸에틸에스테르 관련 검색:
(2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Remdesivir Impurity 39
Remdesivir impurity
R-19-impurity 4
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
R-20 impurity 5
Remdesivir Impurity 44
R-18
Remdesivir
2-ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Remdesivir impurity-1
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol




