ChemicalBook >제품 카탈로그 >(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 구조식 이미지

카스 번호:: 1384441-38-6

상품명:: (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

동의어(영문):: O-Demethyl apremilast;Apremilast Impurity K;Apremilast O-Desmethyl;O-Desmethyl Apremilast;Apremilast impurity HS093311;Apremilast Impurity 4 (O-Desmethyl Apremilast);N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide;N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide;(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-

CBNumber:: CB23145520

분자식:: C21H22N2O7S

포뮬러 무게:: 446.47

MOL 파일:: 1384441-38-6.mol

속성

안전

용도

공급 업체 48

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 속성

끓는 점: 765.2±60.0 °C(Predicted)

밀도: 1.450±0.06 g/cm3(Predicted)

저장 조건: -20°C

용해도: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml

물리적 상태: 결정성 고체

산도 계수 (pKa): 9.80±0.31(Predicted)

안정성: 흡습성

InChIKey: PEUJABWEZWJNBO-MRXNPFEDSA-N

SMILES: C(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(O)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P271	옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352	피부에 묻으면 다량의 물로 씻으시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P312	불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P321	(…) 처치를 하시오.
P332+P313	피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P337+P313	눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
P403+P233	용기는 환기가 잘 되는 곳에 단단히 밀폐하여 저장하시오.
P405	밀봉하여 저장하시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	0
2		0

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide C화학적 특성, 용도, 생산

용도

N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide is a related compound of Apremilast (A729700), which is?an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide may be a useful compound for determining metabolic clearance of apremilast. Apremilast Impurity 7

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 준비 용품 및 원자재

원자재

준비 용품

(S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 공급 업체

글로벌( 48)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32432	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24727	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3681	58
Shenzhen ruikai de biotechnology co., ltd.	0755-61348847 17820674378	2682116078@qq.com	China	7843	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-010-52878169 15801002657	sales@bjcomparison.com	China	5011	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18234	56
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 0086-15250997978	1511893459@qq.com	China	4836	55

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 관련 검색:

3-아세트아미도프탈산 (S)-1-(3-에톡시-4-메톡시페닐)-2-(메틸술포닐)에틸라민N-아세틸-L-류신염 1,3-디옥소-2-이소인돌린아세트산 [[p-(2-메톡시에틸)페녹시]메틸]옥시란 (S)-1-(3-에톡시-4-메톡시페닐)-2-(메틸술포닐)에탄민 3-옥소-1,3-디히드로-벤조[c]이속사졸-4-카르복실산 2-CHLORO-4'-하이드록시아세토페논 3-에톡시-4-메톡시-알파-[(메틸설포닐)메틸]-벤젠메타나민 3-에톡시-4-메톡시벤조산 1,2-벤젠디카르복실산,3-(히드록시아미노)-(9CI) (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Apremilast Apremilast 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone APST-ZA Apremilast Impurity 2 Apremilast Impurity 9 Apremilast Impurity 1