2-Aminoadenosine
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2-Aminoadenosine 속성
- 녹는점
- 241-243°C (dec.)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 산성 용액약간 용해됨, 가열, 초음파 처리), DMSO(약간 용해됨, 초음파 처리), 에탄올
- 산도 계수 (pKa)
- 13.10±0.70(Predicted)
- 끓는 점
- 798.5±70.0 °C(Predicted)
- 밀도
- 2.25±0.1 g/cm3(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 황백색까지
- InChI
- InChI=1S/C10H14N6O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H4,11,12,14,15)/t3-,5-,6-,9-/m1/s1
- InChIKey
- ZDTFMPXQUSBYRL-UUOKFMHZSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3C(=C(N=C(N)N=3)N)N=C2)[C@H](O)[C@@H]1O
- CAS 데이터베이스
- 2096-10-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 안전지침서 | 24/25 | ||
|---|---|---|---|
| HS 번호 | 29389090 |
2-Aminoadenosine C화학적 특성, 용도, 생산
개요
2-Aminoadenosine is a known analogue of adenosine that engages in three hydrogen bonds of the W-C type, adding considerable stability to the double helix.화학적 성질
White Powder용도
2-Aminoadenosine is a nucleoside analog as inhibitor or substrate of adenosine kinase from M. tuberculosis. It is also used to synthesize 2′-O-methyl and 3′-O-methyl Guanosine.정의
ChEBI: 2-Aminoadenosine is a purine nucleoside.Synthesis
The synthesis of 2-aminoadenosine (2-AA): Assays were performed in 5 and 10% of aprotic dipolar co-solvents, at 60°C, twelve units/ml cell lysate were added to 150 ml of a solution kept thermostatically at 60 °C, and having the following composition of substrate solutions: 15mM Uridine/2 ' -Deoxyuridine,5 mM 2,6-Diaminopurine, and 30 mM potassium phosphate buffer, pH 7. After 5 hours, the reaction mixture was filtered by centrifugation at 2000 x g for 30 min, at 4°C, through an Amicon ultra-4 Centrifugal Filter Devices (Millipore, Bedford, MA) with a 3000-Da cutoff, and the filtrate was recovered.
참고 문헌
Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism. DOI: 10.1039/B708736EAn Efficient Process for Synthesis of 2′-O-methyl and 3′-O-methyl Guanosine from 2-aminoadenosine Using Diazomethane and the Catalyst Stannous Chloride. DOI: 10.1080/15257770500544529
2-Aminoadenosine 준비 용품 및 원자재
원자재
준비 용품
2-Aminoadenosine 공급 업체
글로벌( 374)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 |
sales@capot.com | China | 29735 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21614 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29847 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 21193 | 58 |
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 |
yunbiochem@126.com | China | 321 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 |
sales@amoychem.com | China | 6369 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 1169 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14332 | 58 |
2-Aminoadenosine 관련 검색:
뉴클레오시드포스포릴라제박테리아 3′,5′-사이클릭아데닐산 구아노신 아데노신 아데닌 자료없음 아데노신 삼인산 Na염 아데노신 트라이포스파타아제 5'-구아닐산 2-아미노-2'-O-메틸아데노신 2, 6-디아미노푸린 8-(6-AMINOHEXYL)아미노-아데노신5'-단일인산리튬염 8-(2-아미노에틸)아미노아데노신-3',5'-환형모노포스페이트 2-(6-아미노헥실)아미노아데노신-3',5'-고리모노포스페이트 8-(6-AMINOHEXYL)아미노아데노신5'-TRIPHOSPHATELITH 3'-아미노-D-아데노신 8-(4-아미노부틸)아미노아데노신-3',5'-고리형모노포스페이트 8-AHA-캠프