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ChemicalBook >제품 카탈로그 >생화학 공학>아미노산과 유도체>리신 유도체>FMOC-LYS(BOC)(ME)-OH

FMOC-LYS(BOC)(ME)-OH

FMOC-LYS(BOC)(ME)-OH 구조식 이미지
카스 번호:
951695-85-5
상품명:
FMOC-LYS(BOC)(ME)-OH
동의어(영문):
Fmoc-Lys(Me,Boc);FMOC-LYS(ME,BOC)-OH;FMOC-LYS(BOC)(ME)-OH;FMOC-L-LYS(BOC, ME)-OH;Boc-L-Lys(Fmoc)(Me)-OH;FMOC-LYSINE(BOC)(ME)-OH;Fmoc-Lys(Me,Boc)-OH,95%;Fmoc-Lys(Me,Boc)-OH, >=97%;FMOC-LYS(BOC)(ME)-OH USP/EP/BP;Fmoc-Lys(Me,Boc)-OH Novabiochem
CBNumber:
CB3465262
분자식:
C27H34N2O6
포뮬러 무게:
482.57
MOL 파일:
951695-85-5.mol

FMOC-LYS(BOC)(ME)-OH 속성

녹는점
85-87℃
끓는 점
665.4±55.0 °C(Predicted)
밀도
1.200
저장 조건
-20°C
용해도
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
물리적 상태
가루
산도 계수 (pKa)
3.88±0.21(Predicted)
색상
White to off-white
??? (Optical Rotation)
-4°(C=0.01g/ml MEOH)
InChIKey
JHMSFOFHTAYQLS-QHCPKHFHSA-N
SMILES
C(O)(=O)[C@H](CCCCN(C(OC(C)(C)C)=O)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
WGK 독일 WGK 2 water endangering
HS 번호 2924 29 70
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.

FMOC-LYS(BOC)(ME)-OH C화학적 특성, 용도, 생산

개요

Fmoc-lys (BOC) (ME)-OH is a kind of protected form of lysine. Lysine is double-protected by butyloxycarbonyl (BOC) and 9H-fluoren-9-ylmethoxycarbon (FMOC). It is a derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. The Boc protecting group can be removed through the TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.

용도

  1. Heterochromatin protein 1 (HP1) depends on trimethylation of H3 Lys 9; aggregation of chromatines depends on Lys methylation
  2. Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones. Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures. The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.
  3. Fmoc-Lys(Boc, Me)-OH is a novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction.

일반 설명

Fmoc protected N-methylated lysine

참고 문헌

http://www.chempep.com/ChemPep_Products2_Fmoc-Amino-Acid_Fmoc-Lys_Boc_Me_-OH.htm
https://en.wikipedia.org/wiki/Peptide_synthesis
Tung, C. L., et al. "A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation. " Chemical Communications 50.40(2014):5298-300.

FMOC-LYS(BOC)(ME)-OH 준비 용품 및 원자재

원자재

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(methylamino)hexanoic acid 중탄산나트륨(중조) Benzenebutanamide, N-8-quinolinyl- 물 테트라하이드로푸란 디 -Tert- 부틸 디 카보네이트

준비 용품

FMOC-LYS(BOC)(ME)-OH 공급 업체

글로벌( 143)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Adachibio Inc. 		+8108027837258
 sales@adachibio.com Japan 992 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29852 58
Biochempartner 		0086-13720134139
candy@biochempartner.com CHINA 965 58
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034
 CHINA 3904 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 20424 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739
 info@dycnchem.com China 52846 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19908 58

FMOC-LYS(BOC)(ME)-OH 관련 검색:

Fmoc-L-베타-호모아르기닌(Pmc) (s)-3-(fmoc-아미노)-n-트리틸-아디프산6-아미드 FMOC-LYS(ME3)-OH HCL FMOC-LYS(ME)2-OH HCL FMOC-D-LYS(IVDDE)-OH Fmoc-Lys(Trt)-OH FMOC-LYS(DNP)-OH N(ALPHA)-FMOC-N(EPSILON)-DABCYL-L-LYSINE FMoc-Aea-OH Fmoc-N'-Acetyl-L-lysine Fmoc-Lys(Pal-Glu-OtBu)-OH Fmoc-Lys(N3)-OH FMOC-LYS(FMOC)-OH Fmoc-L-Lys(Dde)-OH Fmoc-Lys(Ddiv)-OH FMOC-LYS(BOC)(ISOPROPYL)-OH FMOC-LYS(BOC)(ME)-OH N-ALPHA-FMOC-BETA-(1-BOC-PIPERIDIN-4-YL)-D,L-ALANINE
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