클로로(3-)피오니트릴
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클로로(3-)피오니트릴 속성
- 녹는점
- -52--50 °C (lit.)
- 끓는 점
- 174-176 °C (lit.)
- 밀도
- 1.144 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.438(lit.)
- 인화점
- 168 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 45g/L
- 물리적 상태
- 투명한 액체
- 색상
- 무색 내지 거의 무색
- 수용성
- 4.50g/100mL
- Merck
- 14,2160
- BRN
- 1098454
- CAS 데이터베이스
- 542-76-7(CAS DataBase Reference)
- NIST
- Cl(CH2)2CN(542-76-7)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T+ | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 23-28 | ||
| 안전지침서 | 36/37/39-45 | ||
| 유엔번호(UN No.) | UN 3276 6.1/PG 2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | UG1400000 | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | II | ||
| HS 번호 | 29269095 | ||
| 유해 물질 데이터 | 542-76-7(Hazardous Substances Data) | ||
| 독성 | LD50 orally in mice, rats: 9, 100 mg/kg, Fassett in Industrial Hygiene and Toxicology vol. 2, F. A. Patty, Ed. (Interscience, New York, 2nd ed., 1962) pp 2025-2026 | ||
| 기존화학 물질 | KE-05873 |
클로로(3-)피오니트릴 C화학적 특성, 용도, 생산
화학적 성질
3-Chloropropionitrile is a combustible, colorless liquid with an acrid odor용도
In pharmaceutical and polymer synthesis. Combines the reactivity of a nitrile and an alkyl halide. Because of the cyano group the chlorine atom is more reactive than in ordinary alkyl halides.생산 방법
3-Chloropropionitrile [542-76-7], 3-chloropropanenitrile, b-chloropropionitrile, ClCH2 CH2CN, Mr 89.53, mp-51℃, bp 175 –176℃ (101.3 kPa), n20D 1.4360, d204 1.1573, is a colorless liquid miscible with acetone, benzene, ethanol and diethyl ether. It can be obtained by hydrochlorination of acrylonitrile with hydrochloric acid [49] and is used as an organic intermediate in the synthesis of the H2-receptor famotidine.일반 설명
Colorless liquid with a characteristic acrid odor. Used in pharmaceutical and polymer synthesis.반응 프로필
Toxic gas (hydrogen chloride) is released when the compound is heated above 266 F. When heated to decomposition, 3-Chloropropiononitrile emits very toxic fumes of chlorine- containing compounds and nitrogen oxides. Avoid heat. [EPA, 1998].위험도
Toxic by ingestion, inhalation, and skin contact. Combustible.건강위험
Toxic effects are a result of systemic cyanide poisoning. (Non-Specific -- Cyanide) Few poisons are more rapidly lethal. Average oral lethal dose for hydrogen cyanide is approximately 60-90 mg (corresponds to 200 mg of potassium cyanide). Cause of death is lack of oxygen to the body's cells (especially the brain and heart) as a result of the chemical inhibiting cell enzymes.화재위험
Toxic gas (hydrogen chloride) is released when the compound is heated above 266F. When heated to decomposition, 3-Chloropropiononitrile emits very toxic fumes of chlorine- containing compounds and nitrogen oxides. Avoid heat.잠재적 노출
This material is used in pharmaceutical manufacture and in polymer synthesis.운송 방법
UN3276 Nitriles, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required, Potential Inhalation Hazard (Special Provision 5).비 호환성
Contact with strong oxidizers may cause a fire and explosion hazard클로로(3-)피오니트릴 준비 용품 및 원자재
원자재
준비 용품
클로로(3-)피오니트릴 공급 업체
글로벌( 177)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29852 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 |
export01@shyrchem.com | CHINA | 1319 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49975 | 58 |
| Alfa Chemistry | |
info@alfa-chemistry.com | United States | 2344 | 58 |
| Aston Chemical | 13000000000 |
sales@astonchem.com | United States | 1634 | 58 |
| ShanDong Look Chemical Co.,Ltd. | +8617653113219 |
sales01@sdlookchemical.com | China | 2768 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 9081 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 |
sales01@tairunfaz.com | China | 8051 | 58 |
클로로(3-)피오니트릴 관련 검색:
파모티딘관련화합물B [3-[[[2-(디아미노메틸렌아미노)-4-티아졸릴]메틸]티오]프로피오닐]설파마이드염산염(파모티딘불순물) 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC산메틸에스테르 3-(2-구아니디노-티아졸-4-일-메틸티오)-프로피오니트릴 (S)-((2-구아니디노-4-티아졸릴)메틸이소티오우레아이염산염 비스[(2-구아니디노-4-티아졸릴)메틸]디설파이드 2-(4-(클로로메탄)THIAZOL-2-YL)구아닌 3-[2-(디아미노메틸렌아미노)-1,3-티아졸-4-일메틸술피닐]-N-술파모일프로판아미딘 FaMotidine산불순물 N-DesaMinosulfonyl-N-시아노FaMotidine FaMotidine산불순물메틸에스테르 3-하이드록시-프로피오나미딘 프로피오니트릴 2-클로로프로피오니트릴 (+)-2-클로로프로피오노니트릴 2,2,3-트리클로로프로피오니트릴 3-클로로-2-하이드록시프로피오노니트릴 1-(클로로메틸)사이클로헥산카보니트릴