Psorslidin;psoralidin;Psoralidin-RM;Psoralidin, BR;Psoralidin (6CI);Psoralidin, >=99%;Psoralidin, 10 mM in DMSO;3,9-Dihydroxy-2-prenylcoumestan;3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one;3,9-Dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-benzofuro[3,2-c]chromen-6-one
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
DMSO: 용해성5mg/mL, 투명(가온)
산도 계수 (pKa)
8.70±0.20(Predicted)
물리적 상태
가루
색상
흰색에서 베이지색
InChIKey
YABIJLLNNFURIJ-UHFFFAOYSA-N
안전
위험 및 안전 성명
위험 및 사전주의 사항 (GHS)
WGK 독일
3
HS 번호
2932.20.4500
그림문자(GHS):
신호 어:
Warning
유해·위험 문구:
암호
유해·위험 문구
위험 등급
범주
신호 어
그림 문자
P- 코드
H302
삼키면 유해함
급성 독성 물질 - 경구
구분 4
경고
P264, P270, P301+P312, P330, P501
예방조치문구:
NFPA 704
0
2
0
psoralidin C화학적 특성, 용도, 생산
개요
Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells. Through TNF-related apoptosis-inducing ligand-mediated events, psoralidin at 50 μM can induce the death of HeLa cancer cells. It also can induce apoptosis of androgen-dependent (LNCaP, C4-2B) and androgen-independent (DU-145, PC-3) prostate cancer cells and inhibit the growth of PC-3 xenograft tumors in nude mice.
용도
Psoralidin is an antibacterial and antioxidant reagent.
정의
ChEBI: A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 3 and 9 and a prenyl group at position 2 respectively.
