LOXO-292

LOXO-292 구조식 이미지
카스 번호:
2222755-14-6
상품명:
LOXO-292
동의어(영문):
RET-IN-1;RET IN 1,RETIN1;selpercatinib(LOX0292);Pyrazolo[1,5-a]pyridine-3-carbonitrile, 4-[5-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-2-pyrazinyl]-6-[(2R)-2-morpholinylmethoxy]-
CBNumber:
CB44668147
분자식:
C29H31N9O3
포뮬러 무게:
553.61
MOL 파일:
2222755-14-6.mol

LOXO-292 속성

밀도
1.49±0.1 g/cm3(Predicted)
저장 조건
Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
용해도
DMSO에 용해됨
산도 계수 (pKa)
8.23±0.40(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
InChIKey
GTQISTQEBXXLPC-UBVWURDFSA-N
SMILES
C12=C(C#N)C=NN1C=C(OC[C@@H]1OCCNC1)C=C2C1=NC=C(N2CC3CC(N3CC3=CC=C(OC)N=C3)C2)N=C1

안전

LOXO-292 C화학적 특성, 용도, 생산

개요

RET-IN-1 is an oral and selective investigational drug in clinical development for the treatment of patients with cancers that harbor abnormalities in the rearranged during transfection (RET) kinase.

LOXO-292 준비 용품 및 원자재

원자재

준비 용품


LOXO-292 공급 업체

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