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(S)-Pro-xylane C화학적 특성, 용도, 생산
개요
(S)-Pro-xylane is the S-enantiomer of Pro-xylane. Pro-xylane, a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis.
용도
(S)-Pro-xylane (Hydroxypropyl tetrahydropyrantriol) is a C-glycoside, a
xylose derivative, that stimulates the production of glycosaminoglycans
(GAGs) and heparan sulfate proteoglycans (HSPGs) and induces a higher
deposition of proteins in basement membranes and dermal-epidermal
junctions (DEJs). Pro-xylane is used to maintain skin elasticity and
improve skin aging.
Synthesis
In the autoclave, add 461g of intermediate 2,5 liters of isopropanol sequentially, seal the autoclave, replace the nitrogen 3 times, hydrogen displace 1 time, and then dissolve the catalyst [RuCl(cymene)(S-BINAP)] Cl (300mg) in 300mL of isopropanol solution underH2atmosphere, carefully add it to the autoclave, continue to fill hydrogen to 50kgf/cm2, and then heat up to about 60 °C, After stirring the reaction for 6h, stop the reaction, remove the material, and cool down the crystals to obtain βS-type Boseine products.The final product (S)-Pro-xylane can be obtained.
