Nervonic acid
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Nervonic acid 속성
- 녹는점
- 42-43 °C (lit.)
- 끓는 점
- 459.84°C (rough estimate)
- 밀도
- 0.9009 (rough estimate)
- 굴절률
- 1.4806 (estimate)
- 인화점
- >230 °F
- 저장 조건
- -20°C
- 용해도
- 클로로포름(약간 용해됨), 헥산(매우 소량)
- 산도 계수 (pKa)
- 4.78±0.10(Predicted)
- 물리적 상태
- 액체
- 색상
- 흰색에서 연한 노란색
- 생물학적 소스
- plant
- BRN
- 1728551
- InChI
- InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
- InChIKey
- GWHCXVQVJPWHRF-KTKRTIGZSA-N
- SMILES
- C(O)(=O)CCCCCCCCCCCCC/C=C\CCCCCCCC
- LogP
- 10.890 (est)
- CAS 데이터베이스
- 506-37-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Nervonic acid C화학적 특성, 용도, 생산
개요
Nervonic acid, also known as shark oil acid, is a monounsaturated omega-9 fatty acid that exists in nerve tissue and fish oil. It was first discovered in shark brain and is a component of cerebroside, the main source of in shark brain and shark oil. It is also found in the sphingolipids of white matter in human brain.출처
Nervonic acid is abundant in King Salmon ( Chinook ) with 140 mg/100g, yellow mustard seed 83 mg/100g , flax seed 64 mg/ 100g, Sockeye salmon 40 mg/100g, sesame seed 35mg/100g, and macademia nuts 18 mg/100g.정의
ChEBI: Nervonic Acid is a monounsaturated fatty acid with a 24-carbon backbone and the sole double bond originating from the 9th carbon from the methyl end, with this bond in the cis- configuration. It is a metabolite found in the aging mouse brain.제조 방법
Nervonic acid was shown to be identical with selachaleic acid isolated from whale oils. It is obvious that nervonic acid is probably the cis form of erucylacetic acid. Erucylacetic acid has been prepared from erucyl alcohol through the bromide and malonic ester synthesis and has been shown to be identical with nervonic acid obtained from hydrolysis of the cerebroside isolated from human brains.Nervonic acid is also produced from oleic acid, that undergoes three consecutive chain elongation steps, catalyzed by elongases.Two carbon units are added in each step, with production of gadoleic acid, erucic acid, and finally, nervonic acid.
benefits
Nervonic acid (NA, a monounsaturated long-chain fatty acid) has been found to alleviate neurodegeneration. In humans, abnormal NA levels are closely associated with a higher risk of developing neurological or psychiatric disorders such as psychosis, schizophrenia, or attention deficit disorder. Studies have shown that NA treatment can improve cognitive function, prevent demyelination and oligodendrocyte loss or apoptosis, improve cerebral blood flow, and upregulate brain-derived neurotrophic factor and myelin basic protein genes. In addition, NA can not only stimulate adipogenesis by regulating signaling pathways in human MSCs, but also improve the results of fat transplantation by reducing inflammation and stimulating angiogenesis.Biological Functions
Nervonic acid is the only dual-action miracle substance that can repair nerve fibers that unblock damaged nerve pathways in the brain and promote nerve cell regeneration. It has been identified as important in the biosynthesis of nerve cell myelin. It is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.일반 설명
Nervonic acids are the products of desaturation and elongation processes of various fatty acids such as palmitic acid, stearic acid, oleic acid, etc.Nervonic acid 준비 용품 및 원자재
원자재
준비 용품
Nervonic acid 공급 업체
글로벌( 397)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shangdong Yuanlitai Nutratech Co.,ltd | +8618782242822 |
tatiana@yltnutra.com | China | 8 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 |
1713330907@QQ.com | China | 2639 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 455 | 58 |
| S&Y Biochem Co.,Ltd | +86-17774091612; +8617774091612 |
marketing@sybiochem.com | China | 296 | 58 |
| WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?) | +86-86-057182358004 +8613588879771 |
info@weitai-pharmaceutical.com | China | 61 | 58 |
| Jinan Ruitong Biotech Co., Ltd. | +86-16615778970 +86-16615778970 |
info@ritonbio.com | China | 511 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 |
Sibel@chuanghaibio.com | China | 8772 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 +86-18829239519 |
sales06@tgybio.com | China | 898 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5251 | 58 |
| HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 |
sales2@runyanpharma.com | China | 302 | 58 |