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CAY10499

CAY10499 구조식 이미지

카스 번호:: 359714-55-9

상품명:: CAY10499

동의어(영문):: CAY10499;CAY10499 Exclusive;MAGL-IN-5, 10 mM in DMSO;QTENHWTVRQKWRI-UHFFFAOYSA-N;Benzyl (4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl)carbamate;Inhibitor,inhibit,MAGLIN5,MAGL IN 5,FAAH,Fatty acid amide hydrolase,Monoacylglycerol lipase,MAGL;Carbamic acid, N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-, phenylmethyl ester

CBNumber:: CB62590413

분자식:: C18H17N3O5

포뮬러 무게:: 355.34

MOL 파일:: 359714-55-9.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 49

CAY10499 속성

밀도: 1.31±0.1 g/cm3(Predicted)

저장 조건: 2-8°C

용해도: DMSO에 용해됨

물리적 상태: 결정질 고체

산도 계수 (pKa): 13.31±0.70(Predicted)

색상: Off-white to yellow

InChI: InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)

InChIKey: QTENHWTVRQKWRI-UHFFFAOYSA-N

SMILES: C(OCC1=CC=CC=C1)(=O)NC1=CC=C(N2N=C(OC)OC2=O)C=C1C

안전

CAY10499 C화학적 특성, 용도, 생산

개요

CAY10499 is a non-selective lipase inhibitor (IC₅₀s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). It also inhibits ATGL, DAGLa, ABHD6, and CES1 by 95, 60, 90, and 95%, respectively, when used at a concentration of 5 mM. CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC₅₀s = 4.2, 46, 106.7, and 79.8 μM, respectively). In vivo, CAY10499 reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats.

CAY10499 준비 용품 및 원자재

원자재

준비 용품

CAY10499 공급 업체

글로벌( 49)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32434	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39032	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Shanghai Beckham Medical Technology Co., Ltd	021-13816613772 13816613772	huahero21@sina.com	China	2175	55
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4716	58
Nantong Hi-Future Biotechnology Co., Ltd	18051384581	sales@chemhifuture.com	China	3210	58