Thymopentin

Thymopentin 속성

Thymopentin C화학적 특성, 용도, 생산

개요

Thymopentin is a kind of peptide. Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. Thymopentin is capable of modulating the immune response. It is a fragment of the thymopoietins (TMPOs) which is a family of nuclear protein. Studies have shown that Thymopentin is capable of affecting the function of T cells and monocytes monitored by increased cGMP level and the triggering of cellular signaling. It is also capable of improve an imbalanced immune system. As an immunomodulating agent, it is clinically used in the treatment of autoimmune diseases such as atopic dermatitis, chronic lymphocytic leukemia, Sezary’s syndrome, rheumatoid arthritis and decreased immune competency. Recent study has also shown that its immuno-modulating effect can also help fight against the infection of mycobacterium tuberculosis.

용도

Thymopentin Acetate (TP-5) is a synthetic immunomodulating pentapeptide.

Clinical Use

Thymopentin is a synthetic, immunomodulating pentapeptide, representing the active fragment of the thymus hormone, thymopoietin. Thymopentin induces phenotypic differentiation and maturation of T-cells. It appears of value in the treatment of primary immune deficiency, rheumatoid arthritis, atopic dermatitis, sarcoidosis and a variety of other diseases with manifestations of disturbed immune balance.

참고 문헌

Zhang, Yan, et al. "Novel thymopentin release systems prepared from bioresorbable PLA–PEG–PLA hydrogels." International journal of pharmaceutics 386.1 (2010): 15-22.
Gonser, S., E. Weber, and G. Folkers. "Peptides and polypeptides as modulators of the immune response: thymopentin—an example with unknown mode of action." Pharmaceutica Acta Helvetiae 73.6 (1999): 265-273.
Wang, Ying, et al. "Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity." Biomaterials 35.9 (2014): 3102-3109.

Thymopentin 준비 용품 및 원자재

원자재

준비 용품

Thymopentin 공급 업체

공급자	전화	이메일	국가	제품 수	이점
ZHEJLANG HUADI PHARMACEUTICAL GROUP CO, LTD.	0571-81061160 18268059989	3343284820@qq.com	China	55	58
Hubei xinghengkang Chemical Technology Co., Ltd	027-88878869 18162384755	969094702@qq.com	China	55	58
ZHEJIANG HUAJUN PHARMACEUTICAL CO., LTD	0571-17315361885 17315361885	15007824@QQ.COM	China	225	58
Nanjing Nor Biotechnology Co., Ltd	17768782665 17768782665	1711908659@qq.com	China	204	58
Sichuan Hantong Kuntai Biotechnology Co., Ltd.	19150383347 19150383347	hantongkuntai@foxmail.com	China	426	58
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	5996	61
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2110	70

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