2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 속성
- 끓는 점
- 479.3±45.0 °C(Predicted)
- 밀도
- 1.126±0.06 g/cm3(Predicted)
- 저장 조건
- under inert gas (nitrogen or Argon) at 2–8 °C
- 산도 계수 (pKa)
- 8.14±0.42(Predicted)
- 외관
- Light brown to black Solid
- InChI
- InChI=1S/C17H28N4O/c1-19-9-11-21(12-10-19)14-5-7-20(8-6-14)15-3-4-16(18)17(13-15)22-2/h3-4,13-14H,5-12,18H2,1-2H3
- InChIKey
- WDQZQPCYVLHWRA-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(N2CCC(N3CCN(C)CC3)CC2)C=C1OC
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 유해·위험 문구: |
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| 예방조치문구: |
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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline C화학적 특성, 용도, 생산
개요
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline is a cycloalkylamine analogue that can be used as a component of organic synthesis intermediates for the synthesis of the active compound ASP3026. ASP3026 is an orally available receptor tyrosine kinase anaplastic lymphoma kinase (ALK) small molecule inhibitor with promising anti-tumour and apoptosis-inducing effects, which has been used in the study of solid tumours, B-cell lymphomas, advanced malignant tumours, interstitial lymphoma kinase-positive and proto-oncogene tyrosine protein kinase ROS-positive therapy.용도
[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine is an intermediate of Brigatinib which is a medicine used to treat cancer that suppresses epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK).2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 준비 용품 및 원자재
원자재
준비 용품
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 공급 업체
글로벌( 194)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Enki Biopharmaceuticals (Shanghai) Limited | +86-0086-2157680326 +8613916707528 |
yusu@enkibiopharma.com | China | 51 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20175 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21620 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 340 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29852 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 |
sales@tianpharm.com | CHINA | 304 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9636 | 58 |