장기간 또는 반복 노출되면 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킬 수 있음
특정 표적장기 독성 - 반복 노출
구분 2
경고
P260, P314, P501
예방조치문구:
P260
분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P314
불편함을 느끼면 의학적인 조치·조언을 구하시오.
P501
...에 내용물 / 용기를 폐기 하시오.
Tenapanor hydrochloride C화학적 특성, 용도, 생산
용도
Tenapanor (AZD1722) HCl is a potent, orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor HCl reduces intestinal phosphate absorption predominantly through the reduction of passive paracellular phosphate flux. Tenapanor HCl has the potential to be used in research on hyperphosphatemia.
Mechanism of action
Tenapanor hydrochloride is a minimally absorbed small molecule sodium/hydrogen exchange isomer 3 (NHE3) inhibitor. NHE3 is involved in the uptake of sodium ions and water into the intestinal lumen, and by inhibiting NHE3, tenapanor is expected to reduce sodium absorption and increase fecal sodium and fluid excretion.
