PICEATANNOL
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PICEATANNOL 속성
- 녹는점
- 223.0-227.0 °C
- 끓는 점
- 108°C/0.04mmHg(lit.)
- 밀도
- 1.1245 (rough estimate)
- 굴절률
- 1.5190 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- H2O: 0.5 mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 9.17±0.10(Predicted)
- 색상
- 연한 황갈색에서 노란색까지
- 수용성
- H2O: 0.5mg/mL
DMSO: 10mg/mL
ethanol: 10mg/mL
- 최대 파장(λmax)
- 323nm(MeOH)(lit.)
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 2개월 동안 보관할 수 있습니다.
- InChI
- InChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+
- InChIKey
- CDRPUGZCRXZLFL-OWOJBTEDSA-N
- SMILES
- C1(O)=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C=C1O
- LogP
- 2.690 (est)
안전
| 안전지침서 | 24/25 | ||
|---|---|---|---|
| WGK 독일 | 3 | ||
| HS 번호 | 29072990 |
PICEATANNOL C화학적 특성, 용도, 생산
화학적 성질
yellow to golden or green crystalline powder용도
A human metabolite of Resveratrol (R150000). Piceatannol is strong anti-oxidant.정의
ChEBI: A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.일반 설명
A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC50 = 3 μM), PKC (IC50 = 8 μM), MLCK (IC50 = 12 μM). In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling. Also inhibits wheat embryo Ca2+-dependent protein kinase (CDPK) (IC50 = 19 μM), and p72syk (IC50 = 10 μM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations. Also possesses anti-leukemic properties. Reported to activate sirtuins and promote the survival of eukaryotic cells.생물학적 활성
Anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56 lck and syk protein tyrosine kinases and inhibits TNF-induced NF- κ B activation and gene expression. Synthesis results from conversion of resveratrol (5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol ) by cytochrome P450 1B1.PICEATANNOL 준비 용품 및 원자재
원자재
Benzene, 4-[(1E)-2-[3,5-bis(phenylmethoxy)phenyl]ethenyl]-1,2-bis(phenylmethoxy)-
(E)-3,3',4,5'-테트라메톡시스틸벤
5-[(E)-2-(3,5-디메톡시페닐)에테닐]-2-메톡시-페놀
레스베라트롤
4-[(E)-2-(3,5-디메톡시페닐)에테닐]-2-메톡시-페놀
준비 용품
PICEATANNOL 공급 업체
글로벌( 427)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 |
abby@chuanghaibio.com | China | 8773 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 |
1022@dideu.com | China | 3995 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 +86-18829239519 |
sales06@tgybio.com | China | 898 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5251 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20185 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 453 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 |
niki@zlchemi.com | China | 7245 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21620 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
PICEATANNOL 관련 검색:
3,5-DIHYDROXY-4'-브로모틸벤 트랜스레스베라트롤4O-bD-글루쿠로나이드 시스레스베라트롤 트랜스/시스레스베라트롤-D4 CIS-트리메톡시스틸벤 트랜스레스베라트롤3-ObD-글루쿠로나이드 4'-메톡시레스베라트롤 레스베라트롤-13C6 1-O-레불리노일레스베라트롤디아세테이트 레스베라트롤3-설파트-4'글루쿠로니드 트랜스레스베라트롤3-황산염 시스레스베라트롤3-ObD-글루쿠로나이드 트랜스레스베라트롤-3,5-디설페이트 레스베라트롤3,4'디아세테이트 트랜스스틸벤 트랜스-아스트링인 (E)-3,3',4,5'-테트라메톡시스틸벤 3,4-O-이소프로필리덴-3,3',4,5'-테트라히드록시스틸벤