Carbetocin

Carbetocin 구조식 이미지
카스 번호:
37025-55-1
상품명:
Carbetocin
동의어(영문):
Carbetocin Acetate;Pabal;DeaMino-2-O-Methyltyrosine-1-carbaoxytocin;d(COMOT);Duratocin;Lonactene;Depotocin;Carbansin;CARBETOCIN;Carbetoxin
CBNumber:
CB9175745
분자식:
C45H69N11O12S
포뮬러 무게:
988.17
MOL 파일:
37025-55-1.mol

Carbetocin 속성

녹는점
140 - 160°C
알파
D -69.0° (c = 0.25 in 1M acetic acid)
끓는 점
1477.9±65.0 °C(Predicted)
밀도
1.218±0.06 g/cm3(Predicted)
저장 조건
-15°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
가루
산도 계수 (pKa)
13.07±0.70(Predicted)
색상
흰색에서 베이지색
수용성
Soluble to 29.65 mg/ml in water
안정성
흡습성
InChIKey
NSTRIRCPWQHTIA-FOILTOEQNA-N

안전

WGK 독일 3

Carbetocin C화학적 특성, 용도, 생산

용도

Carbetocin is an obstetric drug used to control postpartum hemorrhaging.
A new synthetic analog of oxytocin, carbetocin, is long acting and also has a rapid onset of action. It is an oxytocin receptor agonist and also stimulates milk let down due to its action on oxytocin receptors of myoepithelial cells.

정의

ChEBI: Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue o oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

Biochem/physiol Actions

Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin.

부작용

One of the most commonly reported side effects of Carbetocin is hypotension, or low blood pressure. Another frequently observed side effect is nausea, often accompanied by vomiting. It can also cause headache.

Carbetocin 준비 용품 및 원자재

원자재

준비 용품


Carbetocin 공급 업체

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