mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),National Technical Information Service. Vol. AD691-490,
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H341
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생식세포 변이원성 물질
구분 2
경고
P201,P202, P281, P308+P313, P405,P501
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P201
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P202
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P280
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P308+P313
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P405
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P501
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NFPA 704
0
2
0
1,3-나프탈렌 디올 C화학적 특성, 용도, 생산
개요
1,3-Dihydroxynaphthalene (1,3-DHN) is a multifunctional chemical reagent. Similar to resorcinol, it can be phosphorylated at room temperature using phosphotriamide, though its rate of diphosphorylation is lower. In addition, the 1,3-DHN molecule exhibits fluorescent properties, with absorption spectra peaking at 290 nm and 330 nm, while the emission spectrum shows a peak at 380 nm and a shoulder peak at 425 nm. Non-ionic surfactants significantly enhance the fluorescence intensity of 1,3-DHN, whereas the addition of cationic or anionic additives diminishes its fluorescence intensity.
화학적 성질
orange-pink to brown crystalline powder. 1,3-Naphthalenediol [132-86-5], naphthoresorcinol, mp 124℃, is synthesized by hydrolysis of 1,3-naphthalenediamine with sulfuric acid; by heating 1-amino-3-hydroxy-naphthalene-4-sulfonic acid with acid; or by cyclization of ethyl phenylacetoacetate. It is used as an analytical reagent for sugars and glucuronic acid in urine. It is oxidized in alkaline solution to 2-hydroxy-1,4-naphthoquinone and reacts with ammonia at 140℃ to give 3-amino-1- naphthol and 1,3-naphthalenediamine.
용도
Reagent for sugars, oils, and for glucuronic acid in urine: Forsyth, Nature 161, 239 (1948); Heyns, Kelch, Z. Anal. Chem. 139, 339 (1953).