4-다이메틸아미노피리딘
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4-다이메틸아미노피리딘 속성
- 녹는점
- 112 °C
- 끓는 점
- 162 °C
- 밀도
- 0.906 g/mL at 25 °C
- 벌크 밀도
- 520kg/m3
- 증기압
- 0.169 hPa at 20 °C
- 굴절률
- n20/D 1.431
- 인화점
- 110 °C
- 저장 조건
- Store below +30°C.
- 용해도
- 메탄올: 50mg/mL, 투명
- 물리적 상태
- 세분화된
- 산도 계수 (pKa)
- pKa (20°): 9.7
- 색상
- 황백색에서 노란색까지
- 수소이온지수(pH)
- 11 (60g/l, H2O, 20℃)
- 냄새
- 특유의 냄새
- pH 범위
- 9.7 (10% aq soln)
- 수용성
- 76g/L(25℃)
- Merck
- 14,3389
- BRN
- 110354
- 안정성
- 안정적인. 산, 산화제와 호환되지 않습니다.
- InChI
- 1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3
- InChIKey
- VHYFNPMBLIVWCW-UHFFFAOYSA-N
- SMILES
- CN(C)c1ccncc1
- LogP
- 1.34 at 25℃
- CAS 데이터베이스
- 1122-58-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,C,T+,Xn,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 25-34-24/25-36/37/38-27-36-24-20-61-40-23/24/25-67-66-21/22-11-36/37-22-19 | ||
| 안전지침서 | 36/37/39-45-28A-26-28-36/37-53-27-22-16 | ||
| 유엔번호(UN No.) | UN 2811 6.1/PG 2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | US8400000 | ||
| 자연 발화 온도 | 420 °C | ||
| 위험 참고 사항 | Toxic/Corrosive | ||
| TSCA | TSCA listed | ||
| 위험 등급 | 8 | ||
| 포장분류 | II | ||
| HS 번호 | 29333999 | ||
| 스토리지 클래스 | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
||
| Hazard Classifications | Acute Tox. 2 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Aquatic Chronic 2 Eye Dam. 1 Skin Irrit. 2 STOT SE 1 |
||
| 독성 | LD50 orally in Rabbit: 140 mg/kg LD50 dermal Rabbit 90 mg/kg | ||
| 기존화학 물질 | KE-11197 |
4-다이메틸아미노피리딘 C화학적 특성, 용도, 생산
용도
그것은 유기 합성에서 보편적 인 초 친핵 성의 아 실화 촉매 다.용도
DMAP은 염기성 때문에 무수물과의 에스테르 화, Baylis-Hillman 반응, 하이드로 실릴 화, 트리 틸 레이션, Steglich 재 배열, 베타 - 락탐의 Staudinger 합성 및 기타 여러 가지 반응에 유용한 친 핵성 촉매입니다. 키랄성 DMAP 유사체는 주로 2 급 알콜 및 에반스 보조 유형 아미드의 동 역학적 분석 실험에 사용된다.화학적 성질
White solid용도
4-Dimethylaminopyridine (Valaciclovir EP Impurity G; Valacyclovir USP Related Compound G) is a highly efficient catalyst for acylation reactions.일반 설명
Valacyclovir Related Compound G, also called as 4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.Solubility in organics
4-Dimethylaminopyridine can be soluble in methanol, benzene, ethyl acetate, chloroform, methylene chloride, acetone, and acetic acid. Less soluble in ether, diisopropyl ether, cyclohexane, hexane, and water.Purification Methods
Recrystallise DMAP from toluene [Sadownik et al. J Am Chem Soc 108 7789 1986]. [Beilstein 22 V 112.] § A polystyrene supported version (PS-DMAP) is commercially available.4-다이메틸아미노피리딘 준비 용품 및 원자재
원자재
준비 용품
1-[4-(Trifluoromethyl)pyrimid-2-yl]piperazine
2-히드록시-4-(트리플루오로메틸)피리미딘
2-Chloro-4-(trifluoromethyl)pyrimidine
Docetaxel
1-(2-피롤리디노에틸)피페라진
5-(Trifluoromethyl)-1-methyl-1H-pyrazole
1-tert-Butyl-5-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde
Piperazine-1,4-dicarboxylic acid tert-butyl ester methyl ester
2-Hydrazinyl-1-morpholinoethanone
4-Trifluoromethyl-N-methylaniline 97
1-메틸-3-(트리플루오로메틸)-1H-피라졸
1-아세틸-5-브로모인돌린
N4-Benzoylcytosine
2-Acetylamino-4-methylpyridine
1-TERT-부틸-5-(트리플루오로메틸)-1H-피라졸
Boc-L-beta-Homoproline
베타-(4-아세톡시페닐)프로피온산
2-(Methylthio)-4-(trifluoromethyl)pyrimidine
tert-Butyl 5-formylthiazol-2-ylcarbamate
1-tert-Butyl-4-bromo-5-(trifluoromethyl)-1H-pyrazole
3-Hydrazinyl-1-(4-methylpiperazin-1-yl)propan-1-one
Aniracetam
Mono-methyl succinate
2-Aminoisonicotinic acid
Ethyl 2-Aminoisonicotinate
4-Aminobenzanilide
4-Bromo-5-(trifluoromethyl)-1-phenyl-1H-pyrazole
1-tert-Butyl-3-(trifluoromethyl)-1H-pyrazole
메틸6-[(TERT-BUTOXYCARBONYL)아미노]니코틴산염
4-브로모-1-메틸-3-(트리플루오로메틸)-1H-피라졸
5-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde
2-Acetamidopyridine-3-carboxylic acid
1-tert-Butyl-4-bromo-3-(trifluoromethyl)-1H-pyrazole
3-Hydrazinyl-1-morpholinopropan-1-one
2'-Bromoacetanilide
LIMAPROST
4-Bromo-5-(trifluoromethyl)-1-methyl-1H-pyrazole
2,2,2-Trifluoro-1-(3-(trifluoromethyl)-1-phenyl-1H-pyrazol-4-yl)ethanone
2-Hydrazinyl-1-(4-methylpiperazin-1-yl)ethanone
(2R)-(-)-Glycidyl tosylate
4-다이메틸아미노피리딘 공급 업체
글로벌( 1379)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Kaisai Chemical Co., Ltd | 021-33516722 13701817765 |
kaisaichem@163.com | China | 4604 | 58 |
| JIANGSU B-WIN CHEMICAL INDUSTRY CO.,LTD. | 0510-85840252 400-005-1800 |
843925888@qq.com | China | 29 | 58 |
| Nantong Runfeng Petrochemical Co., Ltd | 66017690 19952660367 |
2143087160@qq.com | China | 2989 | 58 |
| Wuxi QianFeng Chemical Technology Co., Ltd. | 0510-82860650 |
qfhg@qianfengchem.com | China | 25 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 |
anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Unichem Company Ltd.(China) | 0510-82328705 13771137389 |
webmaster@unionchems.com | China | 26 | 58 |
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 |
sdfantai@163.com | China | 904 | 58 |
| Shouguang Jiasheng Chemical Co., Ltd. | 0536-7971999 13583611556 |
sgjiasheng@hotmail.com | China | 300 | 58 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 |
sales@heowns.com | China | 24650 | 60 |
| shandongbaqianhehuagong | 15865655795 |
263501023@qq.com | China | 57 | 58 |