2-Mercapto-5-methoxybenzimidazole manufacturers and suppliers

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE suppliers

Properties

Melting point:: 261-263 °C(lit.)

Boiling point:: 309.4±44.0 °C(Predicted)

Density: 1.2425 (rough estimate)

vapor pressure: 0.001Pa at 25℃

refractive index: 1.5690 (estimate)

storage temp.: 2-8°C

solubility: DMSO (Slightly), Methanol (Sparingly)

form: Powder

pka: 10.13±0.30(Predicted)

color: Off-white to light yellow-brown

Water Solubility: insoluble

Sensitive: Air Sensitive

BRN: 3605123

LogP: 1.52-2.399

CAS DataBase Reference: 37052-78-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P305+P351+P338

Hazard Codes: Xi,Xn

Risk Statements: 36/37/38-37-22

Safety Statements: 26-36

WGK Germany: 3

HazardClass: IRRITANT

HS Code: 29332900

Use

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2- [[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2- [[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

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