8-Hydroxyquinoline manufacturers and suppliers

8-Hydroxyquinoline suppliers

Properties

Melting point:: 70-73 °C(lit.)

Boiling point:: 267 °C752 mm Hg(lit.)

Density: 1.0340

vapor pressure: 0.221Pa at 25℃

refractive index: 1.4500 (estimate)

Flash point:: 267°C

storage temp.: Store below +30°C.

solubility: 0.56g/l

pka: 5.017(at 20℃)

form: Liquid

color: White to pale yellow or light beige

Water Solubility: INSOLUBLE

Sensitive: Light Sensitive

Merck: 14,4843

BRN: 114512

Cosmetics Ingredients Functions: ANTIMICROBIAL
CHELATING

Cosmetic Ingredient Review (CIR): 8-Hydroxyquinoline (148-24-3)

InChI: 1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChIKey: MCJGNVYPOGVAJF-UHFFFAOYSA-N

SMILES: Oc1cccc2cccnc12

LogP: 1.85 at 25℃

CAS DataBase Reference: 148-24-3(CAS DataBase Reference)

IARC: 3 (Vol. 13, Sup 7) 1987

NIST Chemistry Reference: 8-Quinolinol(148-24-3)

EPA Substance Registry System: 8-Quinolinol (148-24-3)

Safety Information

Symbol(GHS): GHS05,GHS06,GHS08,GHS09

Signal word: Danger

Hazard statements: H301-H317-H318-H360D-H410

Precautionary statements: P202-P273-P280-P301+P310-P302+P352-P305+P351+P338

PPE: dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes: Xn,Xi

Risk Statements: 22-68-36/37/38

Safety Statements: 45-36/37/39-26-36

RIDADR: 2811

WGK Germany: 3

RTECS: VC4200000

Hazard Note: Harmful/Irritant

TSCA: TSCA listed

HazardClass: 9

PackingGroup: III

HS Code: 29334990

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Repr. 1B
Skin Sens. 1

Hazardous Substances Data: 148-24-3(Hazardous Substances Data)

Toxicity: An LD50 value of 1,200mg/kg was reported for oral administration of 8-hydroxyquinoline to rats (straidsex unspecified; AAPCO, 1966);a value of 48 mg/kg was reported for intraperitoneal administration to mice (strain/sex unspecxed; Bernstein et al., 1963).

Use

8-Hydroxyquinoline (8HQ) is an intermediate of halogenated quinoline anti-amebic drugs, including quiniodoform, clioquinoline, diiodoquinoline and the like. These drugs exert anti-amebic effects by inhibiting intestinal commensal bacteria, and are effective against amoebic dysentery, but have no effect on extra-intestinal amoebic parasites.8HQ is a small planar molecule with a lipophilic effect and a metal chelating ability. As a result, 8HQ and its derivatives hold medicinal properties such as antineurodegenerative, anticancer, antioxidant, antimicrobial, anti-inflammatory, and antidiabetic activities.

You can find 8-Hydroxyquinoline suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.