Cytarabine manufacturers and suppliers

Cytarabine suppliers

Properties

Melting point:: 214 °C

alpha: D24 +153° (c = 0.5 in water)

Boiling point:: 386.09°C (rough estimate)

Density: 1.3686 (rough estimate)

refractive index: 1.5100 (estimate)

storage temp.: 2-8°C

solubility: H₂O: 50 mg/mL, clear, colorless

pka: pKa 4.3 (Uncertain)

form: crystalline

color: Prisms from EtOH (aq)

Water Solubility: almost transparency

λmax: 272nm(H2O)(lit.)

Merck: 14,2784

BRN: 89175

Stability:: Stable for 1 year as supplied from date of purchase. Solutions in DMSO or water may be stored at -20°C for up to 1 month.

InChI: 1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

InChIKey: UHDGCWIWMRVCDJ-STUHELBRSA-N

SMILES: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O

LogP: -1.808 (est)

CAS DataBase Reference: 147-94-4(CAS DataBase Reference)

EPA Substance Registry System: Cytarabine (147-94-4)

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Warning

Hazard statements: H317-H361fd

Precautionary statements: P202-P261-P272-P280-P302+P352-P308+P313

PPE: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes: Xn,Xi

Risk Statements: 43-63-36/37/38-20/21/22

Safety Statements: 36/37-37/39-36-26

WGK Germany: 3

RTECS: HA5425000

F: 10-23

HS Code: 29349990

Storage Class: 11 - Combustible Solids

Hazard Classifications: Repr. 2
Skin Sens. 1

Hazardous Substances Data: 147-94-4(Hazardous Substances Data)

Toxicity: LD50 oral in rat: > 5gm/kg

Use

cytarabine is currently one of the most effective drugs in clinical treatment of acute non-lymphatic myeloid leukaemia. It is clinically mainly applied to the treatment of the induction stage and maintenance and consolidation phase of acute lymphoblastic leukemia and non-lymphocytic leukemia, the acute transformation phase of chronic myeloid leukemia and malignant lymphoma. in ophthalmology, it is for the treatment of viral conjunctivitis and epidemic keratitis. it also has certain efficacy in the treatment of head and neck cancer, gastrointestinal cancer and lung cancer; in addition, the drug also has inhibitory effect on the proliferation of herpes simplex virus, smallpox virus, and vaccinia virus as well as the immune response of the body.

You can find Cytarabine suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.