Adefovir manufacturers and suppliers

Adefovir suppliers

Properties

Melting point:: >260°C

Boiling point:: 632.5±65.0 °C(Predicted)

Density: 1.88

storage temp.: -20°C

solubility: 0.1 M NaOH: ≥5mg/mL

pka: pKa1 2.0, pKa2 6.8(at 25℃)

form: powder

color: white to beige

InChI: InChI=1S/C8H12N5O4P/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-17-5-18(14,15)16/h3-4H,1-2,5H2,(H2,9,10,11)(H2,14,15,16)

InChIKey: SUPKOOSCJHTBAH-UHFFFAOYSA-N

SMILES: P(COCCN1C2C(N=C1)=C(N)N=CN=2)(=O)(O)O

CAS DataBase Reference: 106941-25-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301

Precautionary statements: P301+P310

Hazard Codes: T

Risk Statements: 25

Safety Statements: 45

RIDADR: 2811

WGK Germany: 3

RTECS: SZ6563500

HazardClass: 6.1

PackingGroup: Ⅲ

HS Code: 29339900

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Acute Tox. 3 Oral

Hazardous Substances Data: 106941-25-7(Hazardous Substances Data)

Limited Quantities: 5.0 kg (11 lbs) (solid)

Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Use

Adefovir (Trade name: Preveon, Hepsera) is a prescription drug used for the treatment of chronic infections of hepatitis B virus. It can be formulated as the pivoxil prodrug adefovir dipivoxil. However, it shows no effect against HIV-1. As a orally administrated acyclic nucleotide analog reverse transcriptase inhibitor, it blocking the reproduction of HBV through inhibiting the reverse transcriptase in the body. One of its advantages over another anti-HBV drug, lamivudine is that it is much harder for the virus to develop resistance to it.

You can find Adefovir suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.