Carbachol manufacturers and suppliers

Carbachol suppliers

Properties

Melting point:: 210 °C (dec.) (lit.)

Density: 1.2798 (rough estimate)

refractive index: 1.5557 (estimate)

storage temp.: Desiccate at RT

solubility: H₂O: 1 g/mL

pka: pKa 4.8 (Uncertain)

form: crystalline

color: white

Water Solubility: 1.0 G/ML

Sensitive: Hygroscopic

Merck: 14,1779

BRN: 3917459

Stability:: Hygroscopic

InChI: 1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H

InChIKey: AIXAANGOTKPUOY-UHFFFAOYSA-N

SMILES: [Cl-].C[N+](C)(C)CCOC(N)=O

CAS DataBase Reference: 51-83-2(CAS DataBase Reference)

NIST Chemistry Reference: Carbachol(51-83-2)

EPA Substance Registry System: Carbachol chloride (51-83-2)

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H300

Precautionary statements: P501-P270-P264-P301+P310+P330-P405

PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes: T

Risk Statements: 25-36/37/38

Safety Statements: 45-36/37/39-28A-26

RIDADR: UN 2811 6.1/PG 2

WGK Germany: 3

RTECS: GA0875000

TSCA: TSCA listed

HazardClass: 6.1

PackingGroup: II

HS Code: 29239000

Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications: Acute Tox. 2 Oral

Hazardous Substances Data: 51-83-2(Hazardous Substances Data)

Toxicity: LD50 in mice (mg/kg): 15 orally, 0.3 i.v. (Molitor)

Use

Carbachol is a miotic and has been used to reduce the intraoculartension of glaucoma when a response cannot beobtained with pilocarpine or neostigmine. Penetration of thecornea is poor but can be enhanced by the use of a wettingagent in the ophthalmic solution. In addition to its topicaluse for glaucoma, carbachol is used during ocular surgery,when a more prolonged miosis is required than can be obtainedwith ACh chloride.

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