Cephalothin manufacturers and suppliers

Cephalothin suppliers

Properties

Melting point:: 160-161 ºC

alpha: D20 +50° (c = 1.03 in acetonitrile)

Boiling point:: 757.2±60.0 °C(Predicted)

Density: 1.4162 (rough estimate)

refractive index: 1.6510 (estimate)

storage temp.: Keep in dark place,Sealed in dry,Room Temperature

solubility: DMSO (Sparingly), Dioxane (Slightly), Methanol (Slightly)

pka: pKa 2.5 (Uncertain)

form: Solid

color: White to Off-White

Water Solubility: 158 MG/L

λmax: 263nm(H2O)(lit.)

Merck: 14,1982

CAS DataBase Reference: 153-61-7(CAS DataBase Reference)

EPA Substance Registry System: Cephalothin (153-61-7)

Safety Information

Symbol(GHS): GHS08

Signal word: Warning

Hazard statements: H317-H334

Precautionary statements: P261-P272-P280g-P285-P302+P352-P304+P341-P333+P313-P342+P311-P363-P403-P501c

RTECS: XI0388000

Hazardous Substances Data: 153-61-7(Hazardous Substances Data)

Toxicity: LD50 intracrebral in mouse: 81mg/kg

REACH Registrations: Active

Use

Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

You can find Cephalothin suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.