Colchicine manufacturers and suppliers

Colchicine suppliers

Properties

Melting point:: 150-160 °C (dec.)(lit.)

alpha: -250 º (c=1, alcohol)

Boiling point:: 522.37°C (rough estimate)

Density: 1.2770 (rough estimate)

refractive index: 1.5614 (estimate)

storage temp.: 2-8°C

solubility: H₂O: 10 mg/mL

pka: 12.36(at 20℃)

form: powder

color: white to yellow with a green cast

Water Solubility: 45 g/L (20 ºC)

Sensitive: Light Sensitive

Merck: 14,2471

BRN: 2228813

BCS Class: 3

Stability:: Stable. Light sensitive. Incompatible with strong oxidizing agents.

Major Application: agriculture

InChI: 1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1

InChIKey: IAKHMKGGTNLKSZ-INIZCTEOSA-N

SMILES: COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O

LogP: 1.300

CAS DataBase Reference: 64-86-8(CAS DataBase Reference)

NIST Chemistry Reference: Colchicine(64-86-8)

EPA Substance Registry System: Colchicine (64-86-8)

Safety Information

Symbol(GHS): GHS06,GHS08

Signal word: Danger

Hazard statements: H300-H340

Precautionary statements: P202-P264-P270-P280-P301+P310-P405

PPE: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes: T+,T,Xi

Risk Statements: 26/28-41-46

Safety Statements: 13-45-36/37/39-28-26-53

RIDADR: UN 1544 6.1/PG 1

WGK Germany: 3

RTECS: GH0700000

TSCA: TSCA listed

HazardClass: 6.1

PackingGroup: I

HS Code: 29399990

Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications: Acute Tox. 2 Oral
Muta. 1B

Hazardous Substances Data: 64-86-8(Hazardous Substances Data)

Toxicity: LD50 in rats (mg/kg): 1.6 i.v. (Rosenbloom, Ferguson); in mice (mg/kg): 4.13 i.v. (Beliles)

Excepted Quantities: Max Inner Pack (1g or 1ml) and Max Outer Pack (300g or 300ml)

Use

Colchicine is present in the poisonous autumncrocus (meadow saffron). It is the major alkaloid of Colchicum autumnale L. and Liliaceae. It was used in poison potions in theancient kingdom of Colchis (Greece). It isused therapeutically as an antineoplast, for thesuppression of gout, and in the treatment ofMediterranean fever. It is used in plant studiesfor doubling chromosome groups.

You can find Colchicine suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.