Cresol manufacturers and suppliers

Cresol suppliers

Properties

Melting point:: -1--2°C

Boiling point:: 88-94°C

Density: 1.04

refractive index: 1.5410 to 1.5440

Flash point:: 82°C

storage temp.: Store at R.T.

form: clear liquid

color: Colorless to Almost colorless

Odor: Sweet, tarry.

Water Solubility: 1.932 g/100 mL

Merck: 14,2579

Dielectric constant: 9.0（Ambient）

Exposure limits: ACGIH:TLV-TWA 20 mg/m3,Inhalable fraction and vapor
OSHA:PEL-TWA 5 ppm (22 mg/m3)
NIOSH:REL-TWA 2.3 ppm

Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.

Cosmetics Ingredients Functions: PERFUMING
ANTIMICROBIAL

Cosmetic Ingredient Review (CIR): Cresol (1319-77-3)

InChI: 1S/3C7H8O/c1-6-2-4-7(8)5-3-6;1-6-3-2-4-7(8)5-6;1-6-4-2-3-5-7(6)8/h3*2-5,8H,1H3

InChIKey: QTWJRLJHJPIABL-UHFFFAOYSA-N

SMILES: Cc1ccc(O)cc1.Cc2cccc(O)c2.Cc3ccccc3O

LogP: 1.950

CAS DataBase Reference: 1319-77-3(CAS DataBase Reference)

EPA Substance Registry System: Cresol (1319-77-3)

Safety Information

Symbol(GHS): GHS05,GHS06,GHS08,GHS09

Signal word: Danger

Hazard statements: H301+H311-H314-H370-H372-H373-H336-H411-H227

Precautionary statements: P501-P273-P270-P260-P210-P271-P264-P280-P370+P378-P391-P308+P311-P361+P364-P303+P361+P353-P301+P330+P331-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405

PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes: T

Risk Statements: 20-24/25-34-52/53-68

Safety Statements: 26-36/37/39-45-61-24/25

RIDADR: UN 2022 6.1/PG II (CRESYLIC ACID)

RIDADR: UN 2076 6.1/PG II (CRESOLS, LIQUID)

RIDADR: UN 3455 6.1/PG II (CRESOLS, SOLID)

OEB: B

OEL: TWA: 2.3 ppm; 10.0 mg/m3

WGK Germany: 1

RTECS: GO5950000

F: 8-23

TSCA: TSCA listed

HazardClass: 6.1(a)

PackingGroup: II

HS Code: 29071219

Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications: Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Aquatic Chronic 3
Eye Dam. 1
Muta. 2
Skin Corr. 1B

Hazardous Substances Data: 1319-77-3(Hazardous Substances Data)

REACH Registrations: Active

Limited Quantities: 100ml (liquid) or 0.5 Kg (solid)

Excepted Quantities: Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)

Use

Reports of adverse reactions to cresol are generally associated with the use of either the bulk material or cresol-based disinfectants, which may contain up to 50% cresol, rather than for its use as a preservative. However, a recent case of cutaneous hypersensitivity reaction to the m-cresol component of an insulin formulation detected via intradermal and patch testing has been reported.Cresol is similar to phenol although it is less caustic and toxic. However, cresol is sufficiently caustic to be unsuitable for skin and wound disinfection. In studies in rabbits, cresol was found to be metabolized and excreted primarily as the glucuronide.A patient has survived ingestion of 12g of cresol though with severe adverse effects.LD50 (mouse, oral): 0.76g/kgLD50 (rabbit, skin): 2g/kgLD50 (rat, oral): 1.45g/kg

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