CYTOCHALASIN E manufacturers and suppliers

CYTOCHALASIN E suppliers

Properties

Melting point:: 206 °C

Boiling point:: 587.59°C (rough estimate)

Density: 1.2415 (rough estimate)

refractive index: 1.6290 (estimate)

storage temp.: -20°C

solubility: DMF: 11 mg/ml; DMF:PBS (pH7.2) (1:30): 0.03 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml

form: White solid.

pka: 11.22±0.70(Predicted)

color: White to off-white

BRN: 1096975

InChIKey: LAJXCUNOQSHRJO-ZYGJITOWSA-N

SMILES: C[C@H]1C\C=C\[C@H]2[C@@H]3O[C@]3(C)[C@@H](C)[C@H]4[C@H](Cc5ccccc5)NC(=O)[C@@]24OC(=O)O\C=C\[C@@](C)(O)C1=O

LogP: 1.920 (est)

Safety Information

Symbol(GHS): GHS06,GHS08

Signal word: Danger

Hazard statements: H300-H310-H330-H361

Precautionary statements: P260-P264-P280-P284-P301+P310-P302+P350

PPE: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes: T+,T

Risk Statements: 26/27/28-63

Safety Statements: 28-36/37-45

RIDADR: UN 1544 6.1/PG 2

WGK Germany: 3

RTECS: HA5360000

F: 10

HazardClass: 6.1(a)

PackingGroup: I

HS Code: 29349990

Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications: Acute Tox. 1 Inhalation
Acute Tox. 2 Dermal
Acute Tox. 2 Oral
Repr. 2

Hazardous Substances Data: 36011-19-5(Hazardous Substances Data)

Use

Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. Despite the common mode of action, there is evidence that individual members display diverse selectivity. Specifically, cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, does not inhibit glucose transport.

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