Diosgenin manufacturers and suppliers

Diosgenin suppliers

Properties

Melting point:: 205-208°C

alpha: D25 -129° (c = 1.4 in CHCl3)

Boiling point:: 473.46°C (rough estimate)

Density: 1.0483 (rough estimate)

refractive index: 1.4700 (estimate)

storage temp.: 2-8°C

solubility: chloroform: 20 mg/mL, clear, slightly yellow

pka: 15.02±0.70(Predicted)

form: Solid

color: White to Pale Yellow

optical activity: -12925 (c 1.4, CHCl3)

Water Solubility: Soluble in chloroform (50 mg/ml), ethanol (83 mg/ml at 25°C), water (<1 mg/ml at 25°C), DMSO (<1 mg/ml at 25°C), and methanol.

Merck: 14,3295

BRN: 94582

Cosmetics Ingredients Functions: SKIN CONDITIONING

InChIKey: WQLVFSAGQJTQCK-VKROHFNGSA-N

SMILES: [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]6(CC[C@@H](C)CO6)O2

LogP: 6.602 (est)

CAS DataBase Reference: 512-04-9(CAS DataBase Reference)

NIST Chemistry Reference: Diosgenin(512-04-9)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H413

Precautionary statements: P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

PPE: Eyeshields, Gloves, type N95 (US)

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36/37-24/25

WGK Germany: 2

RTECS: WH1450000

HS Code: 29329990

Storage Class: 11 - Combustible Solids

Use

Crystallise diosgenin from acetone, and chromatograph it on Al2O3 and elute with *C6H6/Et2O (9:1), then recrystallise it from MeOH. Its solubility is ~4% in H2O and 5% in CHCl3. The acetate crystallises from AcOH with m 198o; and has [] D 20 -119o (pyridine). [Marker et al. J Am Chem Soc 65 1199 1943. Mazur et al. J Am Chem Soc 82 5889 1960, Beilstein 19 IV 862.]

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