Icotinib suppliers
Icotinib
- CAS:
- 610798-31-7
- MF:
- C22H21N3O4
- MW:
- 391.42
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 581℃
- Density
- 1.31
- Flash point:
- 305℃
- storage temp.
- Store at -20°C
- solubility
- insoluble in H2O; ≥129.6 mg/mL in DMSO; ≥14.13 mg/mL in EtOH with ultrasonic
- pka
- 5.32±0.20(Predicted)
- form
- Powder
- color
- White to off-white
- InChIKey
- QQLKULDARVNMAL-UHFFFAOYSA-N
- SMILES
- N(c4cc(ccc4)C#C)c1ncnc2c1cc3c(c2)OCCOCCOCCO3
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- WGK Germany
- WGK 3
- HS Code
- 29339900
- Storage Class
- 11 - Combustible Solids
Use
Icotinib (Conmana?, BetaPharma), an EGFR inhibitor, was approved by the China State FDA in 2011 for the treatment of NSCLC. Icotinib resembles erlotinib in possessing the N-(3-ethylnylphenyl) quinazolin-4-amine core scaffold of erlotinib that binds to the EGFR ATP pocket. An adjacent hydrophobic group was also retained while the solvent exposed two 2-methoxyethyoxysubstituents at the 6- and 7-positions of the quinazoline core were cyclized to afford the tetraoxacyclododecene moiety of icotinib. Efficacy and safety of icotinib as first-line therapy in patients has been evaluated for advanced NSCLC in recent clinical studies.
95 supplier list of "Icotinib"
![N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine](https://img.chemicalbook.com/CompanyLogo/d14090ab-023a-43c8-8c88-79393a6b047720260521173044.jpg)
- Product Name:N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine
- Products Intro:Purity: 95% Min. | Package: 1G;1KG;100KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
$32.00-105.00
- Product Name:Icotinib
- Products Intro:Purity: 100% | Package: 1mg;41USD|2mg;58USD|5mg;97USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Icotinib
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Icotinib
- Products Intro:Purity: 98% | Package: 1g,10g,25g,100g,500g,1kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 528-94-9,AMMONIUM SALICYLATE,Linolenic acid,463-40-1,931-36-2
- Product Name:Icotinib
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials
- Product Name:Icotinib
- Products Intro:Purity: >98% | Package: 300 mg | CustNote: Please reach out to us for more information about custom solutions.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Icotinib
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: Icotinib
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:Icotinib；BPI-2009;Conmana;BPI-2009H
- Products Intro:Package: 1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Icotinib
- Products Intro:Purity: 99 | Package: 5KG;1KG,25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Palmitoylethanolamide,GHK-Cu,Copper tripeptide-1,Nicotinamide Riboside Chloride,NMN,Ergothioneine