KL001 manufacturers and suppliers

KL001 suppliers

KL001

CAS:: 309928-48-1

MF:: C21H22N2O4S

MW:: 398.48

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Properties

storage temp.: 2-8°C

solubility: DMSO: soluble20mg/mL, clear

form: powder

color: white to beige

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

InChI: 1S/C21H22N2O4S/c1-28(25,26)22(15-17-7-6-12-27-17)13-16(24)14-23-20-10-4-2-8-18(20)19-9-3-5-11-21(19)23/h2-12,16,24H,13-15H2,1H3

InChIKey: OQAFDLPAPSSOHY-UHFFFAOYSA-N

SMILES: [S](=O)(=O)(N(CC(O)C[n]2c3c(c4c2cccc4)cccc3)Cc1[o]ccc1)C

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn

Risk Statements: 22

WGK Germany: 3

Storage Class: 11 - Combustible Solids

Hazard Classifications: Acute Tox. 4 Oral

Use

KL001 is a small molecule that specifically interacts with cryptochrome (CRY). KL001 prevented ubiquitin-dependent degrdation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes making it a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.

You can find KL001 suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.