LYCORINE manufacturers and suppliers

LYCORINE suppliers

Properties

Melting point:: 253-255℃ (dec.)

alpha: D16 -129° (c = 0.16 in 98% alc)

Boiling point:: 429.61°C (rough estimate)

Density: 1.53

refractive index: 1.5500 (estimate)

storage temp.: 2-8°C

solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

pka: 13.55±0.40(Predicted)

form: powder

color: White to off-white

optical activity: -12916 (c 0.16, 98% ethanol)

InChI: InChI=1S/C16H17NO4/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19/h3-5,11,14-16,18-19H,1-2,6-7H2/t11-,14-,15,16+/m0/s1

InChIKey: XGVJWXAYKUHDOO-KDMZPGMDSA-N

SMILES: [C@H]1(O)[C@]2([H])C3N(CCC3=C[C@@H]1O)CC1C2=CC2OCOC=2C=1

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301

Precautionary statements: P264-P270-P301+P310-P321-P330-P405-P501

Hazard Codes: T

Risk Statements: 25

Safety Statements: 45

RIDADR: UN 2811 6.1/PG 3

WGK Germany: 3

Use

Lycorine is an analgesic, more so than aspirin, and a hypotensive, as are caranine and galanthine . The analgesic activity exhibited by the Amaryllidaceae alkaloids is attributed to their resemblance to the morphine and codeine skeletons. Lycorine also has antiarrhythmic action, and lycorine hydrochloride is a strong broncholytic. In fact, lycorine shows a relaxant effect on an isolated epinephrine-precontracted pulmonary artery and increases contractility and the rate of an isolated perfused heart. These effects are mediated by stimulation of b-adrenergic receptors.Lycorine also has a strong inhibitory effect on parasite (Encephalitozoon intestinalis) development and antifungal activity against Candida albicans. Additionally, lycorine has antifeedant, antimalarial, emetic, anti-inflammatory, antiplatelet , as well as antifertility activities. Galanthine, in turn, shows mild in vitro activity against Tripanosoma brucei rhodesiense and Plasmodium falciparum.

You can find LYCORINE suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.