Norethindrone manufacturers and suppliers

Norethindrone suppliers

Properties

Melting point:: 205-206 °C (lit.)

Boiling point:: 379.83°C (rough estimate)

alpha: D20 -31.7° (chloroform); D20 -25° (chloroform)

Density: 1.0766 (rough estimate)

refractive index: 1.4800 (estimate)

storage temp.: 2-8°C

solubility: chloroform: ≥50 mg/mL, clear, colorless

form: powder

pka: 13.09±0.40(Predicted)

color: white to off-white

biological source: rabbit

Water Solubility: 7.043mg/L(25 ºC)

Merck: 6697

BRN: 1915671

Specific Activity: 122-165nmol/min·mg

BCS Class: 1

InChIKey: VIKNJXKGJWUCNN-XGXHKTLJSA-N

CAS DataBase Reference: 68-22-4(CAS DataBase Reference)

NIST Chemistry Reference: Norethindrone(68-22-4)

EPA Substance Registry System: Norethisterone (68-22-4)

Safety Information

Symbol(GHS): GHS08,GHS09

Signal word: Danger

Hazard statements: H351-H360FD-H362-H410

Precautionary statements: P202-P260-P263-P264-P273-P308+P313

Hazard Codes: Xn

Risk Statements: 40-36/37/38-20/21/22

Safety Statements: 22-36/37/39-45-37/39-26

RIDADR: UN 3077 9 / PGIII

WGK Germany: 3

RTECS: RC8975000

HS Code: 29144000

Hazardous Substances Data: 68-22-4(Hazardous Substances Data)

Toxicity: LD50 oral in mouse: 6gm/kg

Use

norethindrone, the discovery of the potentprogestin activity of 17α-ethinyltestosterone (ethisterone) and19-norprogesterone preceded the development of these potentprogestins. both are orally active, with the 17α-ethinyl groupblocking oxidation to the less active 17-one. the rich electrondensity of the ethinyl group and the absence of the 19-methylgroup greatly enhance progestin activity. both compoundswere of great importance as progestin components of oralcontraceptives, although currently, use of norethynodrel isminimal. norethindrone, usp, and norethindrone acetate,usp, are widely used for all the usual indications of the progestins,as well as being components of oral contraceptives.because these compounds retain key features of the testosteronestructure, including the 17β-oh, it is not surprisingthat they possess some androgenic side effects.

You can find Norethindrone suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.